FlyBase Allele Report: Dmel\for[UAS.cWb]

General Information

Symbol

Dmel\for^UAS.cWb

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct b of Wang

FlyBase ID

FBal0246711

Feature type

allele

Associated gene

Dmel\for

Associated Insertion(s)

Carried in Construct

P{UAS-for.P2.W}

Also Known As

UAS-forP2

Key Links

Transgenic product class

wild_type

(Wang et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Wang et al., 2008)

Mutagen

in vitro construct

(Wang et al., 2008)

Progenitor genotype

Carried in construct

P{UAS-for.P2.W}

Cytology

Description

UASt regulatory sequences drive expression of the P2 isoform of for.

(Wang et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

for

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^NP0285

(Peng et al., 2016)

Phenotype Manifest In

wing blade, with Scer\GAL4^NP0285

(Peng et al., 2016)

Detailed Description

Statement

Reference

Expression of for^Scer\UAS.cWb driven by Scer\GAL4^for-NP0285 leads to balloon wing phenotypes.

(Peng et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^NP0285, for^UAS.cWb has visible phenotype, suppressible | partially by Scer\GAL4^NP0285/lola^EP2537

(Peng et al., 2016)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^NP0285, for^UAS.cWb has wing blade phenotype, suppressible | partially by Scer\GAL4^NP0285/lola^EP2537

(Peng et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of lola^EP2537 partially suppresses balloon wing phenotypes seen in flies with for^Scer\UAS.cWb driven by Scer\GAL4^for-NP0285.

(Peng et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

for^UAS.cWb/Scer\GAL4^c819 rescues for^s

(Wang et al., 2008)

for^UAS.cWb/Scer\GAL4^elav.PLu rescues for^s

(Wang et al., 2008)

Scer\GAL4^c205/for^UAS.cWb rescues for^s

(Wang et al., 2008)

Partially rescues

Scer\GAL4^elav.PU/for^UAS.cWb partially rescues Df(2L)ED243

(Peng et al., 2016)

Scer\GAL4^elav.PU/for^UAS.cWb partially rescues for^20-29

(Peng et al., 2016)

Fails to rescue

Scer\GAL4^how-24B/for^UAS.cWb fails to rescue Df(2L)ED243

(Peng et al., 2016)

Comments

Expression of for^Scer\UAS.cWb driven by Scer\GAL4^elav.PU (but not Scer\GAL4^how-24B) partially rescues targeting defects of motor axons of intersegmental nerve b (ISNb) in Df(2L)ED243/Df(2L)ED243 embryos. Expression of for^Scer\UAS.cWb driven by Scer\GAL4^elav.PU partially rescues targeting defects of motor axons of intersegmental nerve b (ISNb) in for^20-29/for^20-29 embryos. Expression of for^Scer\UAS.cWb driven by Scer\GAL4^elav.PUpartially rescues CNS axonal defects associated with the midline crossing in Df(2L)ED243/Df(2L)ED243 embryos.

(Peng et al., 2016)

Pan-neural expression of for^Scer\UAS.cWb via Scer\GAL4^elav.PLu rescues the memory defect in for^s mutants.

Expression of for^Scer\UAS.cWb via Scer\GAL4^c205 is sufficient to restore visual pattern memory in for^s flies.

Expression of for^Scer\UAS.cWb via Scer\GAL4^c819 is sufficient to restore visual pattern memory in for^s flies.

(Wang et al., 2008)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

for^Scer\UAS.cWb

for^UAS.cWb

Name Synonyms

Saccharomyces cerevisiae UAS construct b of Wang

Secondary FlyBase IDs

References (2)

Report Sections

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