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General Information
Symbol
Scer\GAL4c819
Species
S. cerevisiae
Name
FlyBase ID
FBal0126480
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
c819, C819-GAL4
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Insertion components
    P{GawB}c819
    Product class / Tool use(s)
    Expression Data
    Reporter Expression
    distribution deduced from reporter (Gal4 UAS)
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    ring neuron R2

    Comment: expression begins 32 hr APF

    ring neuron R4 | medial | subset

    Comment: expression starts at 32 hr APF

    ellipsoid body | restricted

    Comment: expression starts at 32 hr APF ; expression is in inner part of ellipsoid body

    Additional Information
    Statement
    Reference

    Scer\GAL4c819 drives adult expression in the ellipsoid body and suboesophageal ganglion.

    Scer\GAL4c819 is expressed in some motorneurons along the dorsal midline in some segments of the larval VNC.

    Pupal and adult expression is observed in R2 and medial R4 ring neurons, that arborize in the outer domain of the ellipsoid body.

     
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Inhibition of neural activity in Scer\GAL4c819-expressing neurons (in which expression is suppressed in the ventral nerve cord using Scer\GAL80tsh-GAL80) does not affect sensitivity to (S,Z,Z)-CH503 (a more potent stereoisomer of the gustatory sex pheromone CH503). As in wild type flies, courtship defects are seen in response to (S,Z,Z)-CH503.

    Thermogenetic activation (using TrpA1UAS.(B).cKa at 28[o]C) of Scer\GAL4c819 cells in adults significantly reduces anaesthesia-sensitive medium-term (3 h) aversive olfactory memory, with no effect on short term (2 min) memory or anaesthesia-resistant 3 h memory, compared to controls; activation of a smaller subset of Scer\GAL4c819 (restricted using Scer\GAL80Gad1) does not affect 3 h memory, compared to controls.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Scer\GAL4c819
    Name Synonyms
    Secondary FlyBase IDs
      References (19)