FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\twfUAS.cWa
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General Information
Symbol
Dmel\twfUAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Wang
FlyBase ID
FBal0247646
Feature type
allele
Associated gene
Dmel\twf
Associated Insertion(s)
Carried in Construct
P{UAS-twf.W}
Key Links
Transgenic product class
wild_type
(Wang et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wang et al., 2010)
Mutagen
in vitro construct
(Wang et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-twf.W}
Cytology
Description

UASt regulatory sequences drive expression of twf.

(Wang et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
twf
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of twfScer\UAS.cWa under the control of Scer\GAL4slbo.2.6 in the border cells at 29[o]C results in a mild delay in the migration of the border cells.

      (Wang et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      twfUAS.cWa/Scer\GAL4Act.PU rescues twf110

      (Wang et al., 2010)
      Partially rescues

      twfUAS.cWa/Scer\GAL4C57 partially rescues twf110

      (Wang et al., 2010)

      twfUAS.cWa/Scer\GAL4elav.PU partially rescues twf110

      (Wang et al., 2010)

      twfUAS.cWa/Scer\GAL4ey-OK107 partially rescues twfEP3701

      (Wang et al., 2010)
      Comments

      Expression of twfScer\UAS.cWa under the control of Scer\GAL4C57 partially rescues lethality of twf110 mutant animals. 22% of animals survive to adulthood.

      Expression of twfScer\UAS.cWa under the control of Scer\GAL4elav.PU partially rescues lethality of twf110 mutant animals. 70% of animals survive to adulthood.

      Expression of twfScer\UAS.cWa under the control of Scer\GAL4Act.PU rescues lethality of twf110 mutant animals. 100% of animals survive to adulthood.

      Expression of twfScer\UAS.cWa under the control of Scer\GAL4ey-OK107 partially rescues the crossing over and, in severe cases, fusion of the β lobe of the adult mushroom body in twfEP3701 mutant animals.

      Pre-synaptic expression of twfScer\UAS.cWa under the control of Scer\GAL4elav.PU completely rescues the enhanced decrease in postsynaptic excitatory junctional potentials in twf110 mutant animals.

      (Wang et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      twfScer\UAS.cWa
      twfUAS.cWa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct of Wang
      Secondary FlyBase IDs
        References (2)