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General Information
Symbol
Dmel\hhUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0248862
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-hh
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of hh.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Under ad libitum nutrition, the adulthood-only expression of hhUAS.cUa under the control of Scer\GAL4bab1-Pgal4-2 (and Gal80[ts] for temporal control of expression) leads to excessive or disorganized basal stalk cells, mis-shaped follicle cells and/or multilayering of the follicular epithelium, as compared to controls. Under starvation, this expression leads to a significant increase in mitotic index of the follicular epithelium, but leads to a less severe multilayering phenotype, as compared to controls.

Compared to controls unresponsive to a 38[o]C probe (without pre-exposure to UV), early third instar larvae with expression of hhScer\UAS.cUa driven by Scer\GAL4ppk.1.9 (but not Scer\GAL4A58 or Scer\GAL4Myo31DF-NP0001) show significant withdrawal responses (genetic allodynia).

In wild type third instar larvae, two dorsal tracheal branches fuse to give rise to two terminal cells with multiple branches; a significantly increased percentage of Scer\GAL4btl.PU>hhScer\UAS.cUa mutant terminal branches have excess (>2) terminal cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Phenotype Manifest In
Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of dispGD2813 significantly suppresses the withdrawal responses to a 38[o]C probe (without pre-exposure to UV) seen in early third instar larvae with hhScer\UAS.cUa over-expressed by Scer\GAL4ppk.1.9.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
hhScer\UAS.cUa
hhUAS.cUa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Unknown
Secondary FlyBase IDs
    References (7)