UASt regulatory sequences drive expression of an inverted repeat.
Expression of hdcGD8578 under the control of Scer\GAL4kn-col85-GAL4 and Scer\GAL4Ugt36A1.PK but not Scer\GAL4Hml.Δ leads to precocious differentiation of lamellocytes within circulating hemocytes (with both Gal4's) and in lymph gland (only with Scer\GAL4kn-col85-GAL4) when compared to control larvae.
Expression under the control of Scer\GAL41407 may result in loss of neuroblasts in the larval brain associated with decreased size of the remaining neuroblasts (depending on the insertion line used).
Expression under the control of Scer\GAL41407 results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls. This may be associated with a reduction in the average size of neuroblasts (depending on the insertion line used).
Adults expressing hdcGD8578 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in viable flies or semi-lethality.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 0% or 20-30% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in planar polarity defects in the orientation of bristles of the notum in 0% or 20-30% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 0%, 10-20% or 30-40% of the Scer\GAL4pnr-MD237-expressing area of the notum, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 may result in mild thorax closure defects, depending on the insertion line used.
Scer\GAL4kn-col85-GAL4, hecaGD8578 has lamellocyte | larval stage phenotype, non-enhanceable by hepGD1461/Scer\GAL4kn-col85-GAL4
Scer\GAL4kn-col85-GAL4, hecaGD8578 has lamellocyte | larval stage phenotype, suppressible | partially by dppUAS.cSa/Scer\GAL4kn-col85-GAL4
Scer\GAL4kn-col85-GAL4, hecaGD8578 has lamellocyte | larval stage phenotype, suppressible | partially by Scer\GAL4kn-col85-GAL4/hhUAS.cUa
Scer\GAL4kn-col85-GAL4, hecaGD8578 has lamellocyte | larval stage phenotype, suppressible | partially by hopKK105136/Scer\GAL4kn-col85-GAL4
Scer\GAL4kn-col85-GAL4, hecaGD8578 has lamellocyte | larval stage phenotype, non-suppressible by hepGD1461/Scer\GAL4kn-col85-GAL4