FB2026_03 , released September 17, 2026
Allele: Dmel\htsGMR.PD
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General Information
Symbol
Dmel\htsGMR.PD
Species
D. melanogaster
Name
FlyBase ID
FBal0248991
Feature type
allele
Associated gene
Dmel\hts
Associated Insertion(s)
Carried in Construct
P{GMR-hts.PD}
Key Links
Transgenic product class
cDNA
(Ohler et al., 2011)
wild_type
(Ohler et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Ohler et al., 2011)
wild_type
(Ohler et al., 2011)
Mutagen
in vitro construct
(Ohler et al., 2011)
Progenitor genotype
Carried in construct
P{GMR-hts.PD}
Cytology
Description

The GMR promoter drives expression of a cDNA encoding the 668 aa 'PD' isoform of the hts product. (Its N-terminal 659 aa are identical to the 'Add1' isoform and it contains most of the Adducin tail, but lacks the very C-terminal part including the MARCKS domain.)

(Ohler et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
GMR
Encoded product / tool
hts
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      htsGMR.PD partially rescues hts01103/Df(2R)BSC26

      (Ohler et al., 2011)

      htsGMR.PD partially rescues htsnull

      (Ohler et al., 2011)
      Comments

      htsGMR.PD eliminates the medulla defects of hts01103 hemizygotes to a large extent.

      htsGMR.PD partially rescues the medulla defects seen in htsnull eyes.

      (Ohler et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      htsGMR.PD
      Name Synonyms
      Secondary FlyBase IDs
        References (1)