FB2026_02 , released June 18, 2026
Allele: Scer\GAL4Gr28b.a.3
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General Information
Symbol
Scer\GAL4Gr28b.a.3
Species
S. cerevisiae
Name
FlyBase ID
FBal0249477
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Gr28b.a-GAL4.3}
Also Known As
Gr28b.a-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Weiss et al., 2011)
Progenitor genotype
Carried in construct
P{Gr28b.a-GAL4.3}
Cytology
Description

A 3kb fragment from the Gr28b a isoform promoter is fused upstream of sequence encoding a GAL4 driver.

(Weiss et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Gr28b
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      gustatory receptor neuron of terminal organ
      (Kwon et al., 2011)
      larval gustatory receptor neuron of the dorsal pharyngeal sense organ
      (Kwon et al., 2011)
      larval gnathal ganglion
      (Kwon et al., 2011)
      larval dorsal pharyngeal gustatory receptor neuron DP1
      (Choi et al., 2016)
      adult stage
      high salt/bitter-sensing neuron | subset of prothoracic tarsal segment 5
      (Ling et al., 2014)
      gustatory receptor neuron | subset of short labellar taste bristle | subset
      (Weiss et al., 2011)
      gustatory receptor neuron | subset of intermediate labellar taste bristle | subset
      (Weiss et al., 2011)
      high salt/bitter-sensing neuron of adult labellum sensillum
      (Weiss et al., 2011)
      intermediate labellar taste bristle I-a

      Comment: isoform Gr28b-RA

      (Weiss et al., 2011, Weiss et al., 2011)
      intermediate labellar taste bristle

      Comment: isoform Gr28b-RA

      (Weiss et al., 2011, Weiss et al., 2011)
      intermediate labellar taste bristle I-b

      Comment: isoform Gr28b-RA

      (Weiss et al., 2011, Weiss et al., 2011)
      short labellar taste bristle S-b

      Comment: isoform Gr28b-RA

      (Weiss et al., 2011, Weiss et al., 2011)
      short labellar taste bristle S-a | intense

      Comment: isoform Gr28b-RA

      (Weiss et al., 2011)
      short labellar taste bristle S-a

      Comment: isoform Gr28b-RA

      (Weiss et al., 2011, Weiss et al., 2011)
      Additional Information
      Statement
      Reference

      ScerGAL4Gr28b.a.3 drives expression in larval gustatory receptor neuron of the epiphysis DP1, where it is coexpressed with ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8, ScerGAL4Gr93a.5, ScerGAL4Gr32a.3.7.PW, ScerGAL4Gr22b.5.8, ScerGAL4Gr39a.a.3.4, ScerGAL4Gr39b.4.4, ScerGAL4Gr22d.3.1, ScerGAL4Gr39b.4.4, ScerGAL4Gr22e.2.5, ScerGAL4Gr39a.b.1, ScerGAL4Gr58b.1, and ScerGAL4Gr59d.4.1.

      (Choi et al., 2016)

      ScerGAL4Gr28b.a.3 drives expression of Gr28b isoform a.

      (Ling et al., 2014)

      ScerGAL4Gr28b.a.3 is expressed in gustatory neurons of all of the bitter-sensitive small labellar taste bristles, and in gustatory neurons of the four posterior-most intermediate labellar taste bristles.

      (Weiss et al., 2011)

      ScerGAL4Gr28a.PT expresses the isoform Gr28b-RA which is found in all of the short and in a few of the intermediate bitter-sensitive sensilla of the labellum.

      (Weiss et al., 2011)

      ScerGAL4Gr28a.PT is expressed in all of the short and in a few of the intermediate bitter-sensitive sensilla of the labellum.

      (Weiss et al., 2011)

      ScerGAL4Gr28b.a.3 drives expression in one gustatory receptor neuron of the larval terminal organ and in one neuron of the dorsal pharyngeal sense organ (DPS or epiphysis). The dorsal organ neuron also expresses ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8, ScerGAL4Gr32a.3.7.PW, ScerGAL4Gr39a.a.3.4, ScerGAL4Gr39a.b.1, ScerGAL4Gr59d.4.1, ScerGAL4Gr9a.6.3, ScerGAL4Gr22e.2.5, ScerGAL4Gr22a.4.2, ScerGAL4Gr28b.e.4.245, ScerGAL4Gr36b.0.9, ScerGAL4Gr36c.2.5, ScerGAL4Gr58b.1, ScerGAL4Gr59a.1.5, ScerGAL4Gr59c.5.5 and ScerGAL4Gr93b.5.3.

      (Kwon et al., 2011)
       
      Marker for
      Reflects expression of
      Gr28b
      (Ling et al., 2014, Kwon et al., 2011, Weiss et al., 2011, Weiss et al., 2011)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ablation of Scer\GAL4Gr28b.a.3-expressing neurons does not affect sensitivity to (S,Z,Z)-CH503 (a more potent stereoisomer of the gustatory sex pheromone CH503). As in wild type flies, courtship defects are seen in response to (S,Z,Z)-CH503.

      (Shankar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Gr28b.a.3
      Name Synonyms
      Secondary FlyBase IDs
        References (12)