FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Gr32a.3.7.PW
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General Information
Symbol
Scer\GAL4Gr32a.3.7.PW
Species
S. cerevisiae
Name
FlyBase ID
FBal0249480
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Gr32a-GAL4.3.7.PW}
Also Known As
Gr32a-GAL4, Gr32a
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Weiss et al., 2011)
Progenitor genotype
Carried in construct
P{Gr32a-GAL4.3.7.PW}
Cytology
Description

A 3.7kb Gr32a promoter fragment is fused upstream of sequence encoding a GAL4 driver.

(Weiss et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Gr32a
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      gustatory receptor neuron of terminal organ
      (Kwon et al., 2011)
      gustatory receptor neuron of terminal organ dorsolateral group
      (Kwon et al., 2011)
      larval gustatory receptor neuron of the dorsal pharyngeal sense organ
      (Kwon et al., 2011)
      larval gustatory receptor neuron of the posterior pharyngeal sense organ
      (Kwon et al., 2011)
      larval gnathal ganglion
      (Kwon et al., 2011)
      larval dorsal pharyngeal gustatory receptor neuron DP1
      (Choi et al., 2016)
      larval dorsal pharyngeal gustatory receptor neuron DP2
      (Choi et al., 2016)
      larval posterior pharyngeal gustatory receptor neuron PP1
      (Choi et al., 2016)
      larval posterior pharyngeal gustatory receptor neuron PP2
      (Choi et al., 2016)
      larval posterior pharyngeal gustatory receptor neuron PP3
      (Choi et al., 2016)
      adult stage
      high salt/bitter-sensing neuron | subset of prothoracic tarsal segment 5
      (Ling et al., 2014)
      high salt/bitter-sensing neuron | subset of prothoracic tarsal segment 4
      (Ling et al., 2014)
      high salt/bitter-sensing neuron | subset of mesothoracic tarsal segment 5
      (Ling et al., 2014)
      high salt/bitter-sensing neuron | subset of mesothoracic tarsal segment 4
      (Ling et al., 2014)
      high salt/bitter-sensing neuron | subset of metathoracic tarsal segment 5
      (Ling et al., 2014)
      high salt/bitter-sensing neuron | subset of metathoracic tarsal segment 4
      (Ling et al., 2014)
      gustatory receptor neuron | subset of short labellar taste bristle | subset
      (Weiss et al., 2011)
      gustatory receptor neuron | subset of intermediate labellar taste bristle | subset
      (Weiss et al., 2011)
      high salt/bitter-sensing neuron of adult labellum sensillum
      (Weiss et al., 2011)
      intermediate labellar taste bristle I-a
      (Weiss et al., 2011, Weiss et al., 2011)
      intermediate labellar taste bristle
      (Weiss et al., 2011, Weiss et al., 2011)
      intermediate labellar taste bristle I-b
      (Weiss et al., 2011, Weiss et al., 2011)
      short labellar taste bristle S-b
      (Weiss et al., 2011, Weiss et al., 2011)
      short labellar taste bristle S-a | intense
      (Weiss et al., 2011)
      high salt/bitter-sensing neuron | subset of adult prothoracic segment
      (Clowney et al., 2015)
      adult abdominal multidendritic neuron | subset
      (Park and Kwon, 2011)
      short labellar taste bristle S-a
      (Weiss et al., 2011, Weiss et al., 2011)
      bitter-sensing neuron | subset
      (Israel et al., 2022)
      adult stage | male
      male-specific neuron | subset
      (Park and Kwon, 2011)
      adult stage | female
      female-specific neuron | subset
      (Park and Kwon, 2011)
      Additional Information
      Statement
      Reference

      Drives expression in a subset of bitter-sensing neurons.

      (FlyBase Curators, 2017)

      ScerGAL4Gr32a.3.7.PW drives expression in the following series of neurons. Larval gustatory receptor neuron of the epiphysis DP1, where it is coexpressed with ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8, ScerGAL4Gr93a.5, ScerGAL4Gr22b.5.8, ScerGAL4Gr39a.a.3.4, ScerGAL4Gr39b.4.4, ScerGAL4Gr9a.6.3, ScerGAL4Gr22d.3.1, ScerGAL4Gr22e.2.5, ScerGAL4Gr28b.a.3, ScerGAL4Gr39a.b.1, ScerGAL4Gr58b.1, and ScerGAL4Gr59d.4.1. Larval gustatory receptor neuron of the epiphysis DP2 where it is coexpressed with ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8, ScerGAL4Gr77a.4 and ScerGAL4Gr93b.5.3. Larval gustatory receptor neuron of the hypopharyngeal organ PP1 and PP2 where it is coexpressed with ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8, ScerGAL4Gr22b.5.8, ScerGAL4Gr39a.a.3.4, ScerGAL4Gr39b.4.4, ScerGAL4Gr39a.d.1.7, ScerGAL4Gr93c.3.8 and ScerGAL4Gr93d.2.4. Larval gustatory receptor neuron of the hypopharyngeal organ PP3 where it is coexpressed with ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8, ScerGAL4Gr28a.PT, ScerGAL4Gr22b.5.8, ScerGAL4Gr39a.a.3.4, ScerGAL4Gr39b.4.4, ScerGAL4Gr39a.d.1.7, ScerGAL4Gr93c.3.8 and ScerGAL4Gr93d.2.4.

      (Choi et al., 2016)

      ScerGAL4Gr32a.3.7.PW drives expression in adult abdominal multidendritic neurons with with dorsal processes extending along the left-right axis, as well as in multidendritic neurons with lateral processes extending anteroposteriorly; these major processes have several protruding dendrites. Expression is also observed in projections to the abdominal ganglion. ScerGAL4Gr32a.3.7.PW also drives expression in neurons innervating the male reproductive organs, mostly innervating the accessory gland; and in neurons innervating the female reproductive organs, mostly innervating the common oviduct, lateral oviducts, or ovaries.

      (Park and Kwon, 2011)

      ScerGAL4Gr32a.3.7.PW is expressed in the gustatory neurons of all of the bitter-sensitive short labellar taste bristles, and the gustatory neurons of all of the intermediate labellar taste bristles.

      (Weiss et al., 2011)

      ScerGAL4Gr32a.3.7.PW is expressed in all of the short and intermediate bitter-sensitive sensilla of the labellum.

      (Weiss et al., 2011, Weiss et al., 2011)

      ScerGAL4Gr32a.3.7.PW drives expression in two gustatory receptor neurons of the larval terminal organ, one of these having its cell body in the dorsal organ ganglion (TO-dorsolateral group). The neuron of the TO-dorsolateral group also expresses ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8 and ScerGAL4Gr10a.3.7. The other terminal organ neuron co-expresses ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8, ScerGAL4Gr28b.e.4.245, ScerGAL4Gr39a.a.3.4, ScerGAL4Gr39a.b.1, ScerGAL4Gr59d.4.1, ScerGAL4Gr9a.6.3, ScerGAL4Gr22e.2.5, ScerGAL4Gr22a.4.2, ScerGAL4Gr28b.a.3, ScerGAL4Gr36b.0.9, ScerGAL4Gr36c.2.5, ScerGAL4Gr58b.1, ScerGAL4Gr59a.1.5, ScerGAL4Gr59c.5.5 and ScerGAL4Gr93b.5.3. Expression of ScerGAL4Gr32a.3.7.PW is also found in two neurons of the dorsal pharyngeal sense organ (DPS or epiphysis) and in two neurons of the posterior pharyngeal sense organ (PPS or hypopharyngeal sense organ).

      (Kwon et al., 2011)
       
      Marker for
      bitter-sensing neuron
      (Israel et al., 2022)
      Reflects expression of
      Gr32a
      (Israel et al., 2022, Clowney et al., 2015, Ling et al., 2014, Kwon et al., 2011, Park and Kwon, 2011, Weiss et al., 2011, Weiss et al., 2011)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ablation of Scer\GAL4Gr32a.3.7.PW-expressing neurons does not affect sensitivity to the gustatory sex pheromone (S,Z,Z)-CH503: as in wild type, courtship defects are seen in these flies in response to (S,Z,Z)-CH503.

      (Shankar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Gr32aGal4
      (Masuzzo et al., 2022)
      Scer\GAL4Gr32a.3.7.PW
      Name Synonyms
      Secondary FlyBase IDs
        References (21)