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General Information
Symbol
Scer\GAL4GMR24C06
Species
S. cerevisiae
Name
FlyBase ID
FBal0250827
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
R24C06
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 2958 base pair fragment from the flanking non-coding or intronic region of ari-1 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

Allele components
Product class / Tool use(s)
Associated Sequence Features
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Scer\GAL4GMR24C06 drives expression mainly in antennal mechanosensory and motor center AMMC PN2 projection neuron, but also drives expression in 5 small antennal mechanosensory and motor center B1 projection neurons, approximately 10 neurons in the adult gnathal ganglion region and in three clusters of approximately 4 cells each in the thoracico-abdominal ganglion.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Inhibition (using Ctet\tetXTNT-LC.UAS) of Scer\GAL4GMR24C06 cells, or the combined set of Scer\GAL4GMR24C06 and Scer\GAL4GMR70G01 cells, significantly diminishes the responses of wedge projection neurons to the onset of wind and slightly reduces the tonic wind response; inhibition of the combined set of Scer\GAL4GMR24C06 and Scer\GAL4GMR45D07 cells does not significantly reduce the responses of wedge projection neurons to the onset of wind or reduce the tonic wind response.

Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus) of Scer\GAL4GMR24C06 cells results in a transient depolarization, followed by hyperpolarization of wedge projection neurons, relative to controls.

Inhibition (using shi1.UAS at 30[o]C) of Scer\GAL4GMR24C06 neurons in adult females does not significantly affect receptivity to mating, compared to controls; in males, courtship pulse song-induced locomotion is not significantly affected, compared to controls.

Thermogenetic activation (using TrpA1UAS.(B).cKa at 27[o]C) of Scer\GAL4GMR24C06 neurons in adult females does not significantly affect receptivity to mating, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4GMR24C06
Name Synonyms
Secondary FlyBase IDs
    References (5)