FB2025_01 , released February 20, 2025
Allele: Dmel\upd3UAS.cMa
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General Information
Symbol
Dmel\upd3UAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Meister
FlyBase ID
FBal0257028
Feature type
allele
Associated gene
Dmel\upd3
Associated Insertion(s)
Carried in Construct
P{UAS-upd3.M}
Also Known As
UAS-Upd3
Key Links
Transgenic product class
wild_type
(Buchon et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Buchon et al., 2010)
Mutagen
in vitro construct
(Buchon et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-upd3.M}
Cytology
Description

UAS regulatory sequences drive expression of upd3.

(Buchon et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
upd3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of upd3Scer\UAS.cMa under the control of Scer\GAL4Myo31DF-NP0001 (using tub-gal80[ts] to limit the time of expression) increases cell proliferation in the adult gut.

      (Wang et al., 2015)

      Ectopic expression of upd3Scer\UAS.cMa in intestinal stem cells (ISCs) under the control of Scer\GAL4esg-NP5130 and Scer\GAL80ts.αTub84B strongly increased both the mitotic index and intestinal epithelium renewal.

      (Buchon et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of EgfrDN.Scer\UAS.cBa blocks the epithelium renewal induced by upd3Scer\UAS.cMa-expression under the control of Scer\GAL4esg-NP5130 and Scer\GAL80ts.αTub84B.

      Co-expression of Ras85DNIG.9375R blocks the epithelium renewal induced by upd3Scer\UAS.cMa-expression under the control of Scer\GAL4esg-NP5130 and Scer\GAL80ts.αTub84B.

      (Buchon et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      upd3Scer\UAS.cMa
      upd3UAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Meister
      Secondary FlyBase IDs
        References (3)