FB2026_02 , released June 18, 2026
Allele: Dmel\RtGEFHMS00741
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General Information
Symbol
Dmel\RtGEFHMS00741
Species
D. melanogaster
Name
FlyBase ID
FBal0257424
Feature type
allele
Associated gene
Dmel\RtGEF
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS00741}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
in vitro construct
(Ni et al., 2010.12.1)
Progenitor genotype
Carried in construct
P{TRiP.HMS00741}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMS00741
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Enhancer of
      Statement
      Reference

      RtGEFHMS00741, Scer\GAL4GMR.PF is an enhancer of visible phenotype of Scer\GAL4GMR.PF, ykiS168A.UAS.YFP

      (Dent et al., 2015)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      RtGEFHMS00741, Scer\GAL4GMR.PF, ykiS168A.UAS.YFP has eye phenotype, suppressible by sdKK108877, Scer\GAL4GMR.PF

      (Dent et al., 2015)
      Enhancer of
      Statement
      Reference

      RtGEFHMS00741, Scer\GAL4GMR.PF is an enhancer of eye phenotype of Scer\GAL4GMR.PF, ykiS168A.UAS.YFP

      (Dent et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of RtGEFHMS00741 enhances the eye overgrowth phenotype caused by expression of ykiS168A.Scer\UAS.T:Avic\GFP-YFP under the control of Scer\GAL4GMR.PF. There is an increase in eye size with folding and convolution of the eye.

      sdKK108877 completely suppresses the eye overgrowth phenotype seen in flies co-expressing RtGEFHMS00741 and ykiS168A.Scer\UAS.T:Avic\GFP-YFP under the control of Scer\GAL4GMR.PF.

      (Dent et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      RtGEFHMS00741
      rtGEFHMS00741
      Name Synonyms
      Secondary FlyBase IDs
        References (4)