FlyBase Allele Report: Dmel\kst[HMS00882]

General Information

Symbol

Dmel\kst^HMS00882

Species

D. melanogaster

Name

FlyBase ID

FBal0257558

Feature type

allele

Associated gene

Dmel\kst

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00882}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00882}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00882

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

photoreceptor cell R8, with Scer\GAL4^GMR.long

(Pojer et al., 2021)

Detailed Description

Statement

Reference

The expression of kst^HMS00882 under the control of Scer\GAL4^GMR.long leads to an increase in the ratio of pale vs yellow photoreceptor cell R8.

(Pojer et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^repo.PU/kst^HMS00882 is a suppressor | partially of lethal - all die during P-stage phenotype of Scer\GAL4^repo.PU, brm^GD4507

(Tegeder et al., 2019)

Other

Statement

Reference

Scer\GAL4^repo.PU, brm^GD4507, kst^HMS00882 has partially lethal - majority die phenotype

(Tegeder et al., 2019)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^GMR.long, kst^HMS00882 has photoreceptor cell R8 phenotype, suppressible by yki^KK109756/Scer\GAL4^GMR.long

(Pojer et al., 2021)

Other

Statement

Reference

Scer\GAL4^GMR.long, kst^HMS00882, yki^KK109756 has photoreceptor cell R8 phenotype

(Pojer et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of yki^KK109756 suppresses the increased ratio of pale vs yellow photoreceptor cells R8 induced by the expression of kst^HMS00882 under the control of Scer\GAL4^GMR.long, even leading to all photoreceptor cells R8 becoming the yellow type.

(Pojer et al., 2021)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

33933