UASt regulatory sequences drive expression of an inverted repeat.
Expression of brmGD4507 under the control of either Scer\GAL4nub.PK or Scer\GAL4en.PU results in unfurled or reduced-size wings with various wing defects. Scer\GAL4Act5C.PI-driven expression is lethal; no overt adult phenotype is observed with either Scer\GAL4ey.PH or Scer\GAL4GMR.PF.
Flies expressing Scer\GAL4c564>brmGD4507 show a significant decrease in survival following Enterobacter cloacae (E. cloacae) or Erwinia carotovora Ecc15 infections when compared with control flies.
Larval brains expressing brmGD4507 under the control of Scer\GAL4wor.PA contain additional type II NB-like cells. Transplantation of this tissue into the abdomens of adult wild type hosts results in tumor formation.
Fewer intestinal stem cells (ISCs) are seen in the posterior midguts of adult flies expressing brmGD4507 under the control of Scer\GAL4esg-NP5130. The number of mitotic cells is also reduced. The cells exhibit a spherical shape compared with the angular shaped control cells. After five or 13 days of brmGD4507 expression no large enterocyte-like cells are observed in ISC clones, indicating that differentiation is not taking place.
Expression of brmGD4507 under the control of Scer\GAL4esg-NP5130 inhibits the increase in intestinal stem cells (ISCs) seen in flies treated with dextran sulfate sodium (DSS).
Expression under the control of Scer\GAL41407 results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls.
Expression under the control of Scer\GAL41407 results in an increase in the number of neuroblasts in the larval brain compared to controls.
Adults expressing brmGD4507 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of brmGD4507 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies or partial lethality, depending on the particular P{GD4507} insertion line used.
Expression of brmGD4507 in the wing under the control of Scer\GAL4salm-459.2 results in the loss of wing veins and wing margin, a reduction in wing size, and ectopic wing hair and sensory organs.
Scer\GAL4nub.PK, brmGD4507 has visible | adult stage phenotype, enhanceable by httint
Scer\GAL4en.PU, brmGD4507 has visible | adult stage phenotype, enhanceable by httint
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG10348HMS02808, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG3662GLC01437, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Argk1HMS02262, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by ptcHMC03872/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/SdcHMC03265
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG6805HMS01290, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by aHMC03685/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by RpS5bGL01864, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/Spn88EaHMS01371
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by LpR1HMS02973, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/dppJF02455
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/dlpHMS00903
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by sobHMS01123/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/kstHMS00882
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Rab27HMS01523, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/Sin1HMS01565
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Rip11HMS01792, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/lin-28HMC03080
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG9386HMS00236, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG4945HMC04884, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by DlstHMC03051, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/visHMS01480
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by BicCHMS01407, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by gsb-nKK100311/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Pkc98EHMS02791, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/ninaDHMC02392
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by sdtHMJ22057/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/kayHMS00254
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG41378GLC01600, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/dpnHMC03154
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG17010HMC04613, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG15803HMC03179, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CanA1JF01871, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/Sik2HMC04153
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/Tm2HMS02260
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Sox14HMS00103/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG40006HMS01170, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by DabHMS02482, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by NetBHMS01177, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Spn43AbHMS02759/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/styHMS01599
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/bnlHMS01046
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by FsHMC04698, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG7409HMC03145, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/aopJF02323
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Hex-AGL00023, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG11593HMS00715, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/nufHMS02751
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG17637KK111636, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG9586KK111397, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by CG4968GL00459, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by par-6KK101015/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by AhcyL1GD14332, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/sliJF01229
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Bub1HMC04961, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by cystHMS01750/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by AgpsHMS01339, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/pydHMS00263
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by acHMC03406/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Sod2HMS00499/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by GluRIIBJF03145, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by InvadolysinGD5576, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Pgant9HMC02984, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Klf15JF02420, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by stjKK101267/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Apc2GD11854, Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/bowlJF02419
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Scer\GAL4repo.PU/gbbHMS01243
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Unc-115aHMS02005/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by unc-104HMC03512/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by muraGL00121/Scer\GAL4repo.PU
Scer\GAL4repo.PU, brmGD4507 has lethal - all die during P-stage phenotype, suppressible | partially by Hsp27HMS00867, Scer\GAL4repo.PU
Scer\GAL4repo.PU, Tm2HMS02260, brmGD4507 has partially lethal - majority live phenotype
Scer\GAL4repo.PU, brmGD4507, gbbHMS01243 has partially lethal phenotype
Scer\GAL4repo.PU, SdcHMC03265, brmGD4507 has partially lethal - majority die phenotype
CG6805HMS01290, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, Spn88EaHMS01371, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, ptcHMC03872 has partially lethal - majority die phenotype
CG4945HMC04884, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, kayHMS00254 has partially lethal - majority die phenotype
LpR1HMS02973, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Rab27HMS01523, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, kstHMS00882 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, gsb-nKK100311 has partially lethal - majority live phenotype
Scer\GAL4repo.PU, brmGD4507, dppJF02455 has partially lethal - majority die phenotype
Rip11HMS01792, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, sdtHMJ22057 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, lin-28HMC03080 has partially lethal - majority die phenotype
DlstHMC03051, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, visHMS01480 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, Sin1HMS01565, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, styHMS01599 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, ninaDHMC02392 has partially lethal - majority die phenotype
CG9386HMS00236, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
RpS5bGL01864, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority live phenotype
Pkc98EHMS02791, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
CG41378GLC01600, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
FsHMC04698, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, dpnHMC03154 has partially lethal - majority die phenotype
CG15803HMC03179, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
CG17010HMC04613, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, Spn43AbHMS02759, brmGD4507 has partially lethal - majority die phenotype
CanA1JF01871, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, Sik2HMC04153, brmGD4507 has partially lethal - majority die phenotype
CG40006HMS01170, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, muraGL00121 has partially lethal - majority live phenotype
Scer\GAL4repo.PU, Sox14HMS00103, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, dlpHMS00903 has partially lethal - majority die phenotype
NetBHMS01177, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
DabHMS02482, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Pgant9HMC02984, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
CG11593HMS00715, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Klf15JF02420, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
GluRIIBJF03145, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
CG4968GL00459, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, nufHMS02751 has partially lethal - majority die phenotype
Hsp27HMS00867, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority live phenotype
Scer\GAL4repo.PU, Sod2HMS00499, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, sliJF01229 has partially lethal - majority die phenotype
CG17637KK111636, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, par-6KK101015 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, pydHMS00263 has partially lethal - majority die phenotype
CG9586KK111397, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, stjKK101267 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, cystHMS01750 has partially lethal - majority die phenotype
Bub1HMC04961, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
InvadolysinGD5576, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, sobHMS01123 has partially lethal - majority live phenotype
CG7409HMC03145, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, Unc-115aHMS02005, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, brmGD4507, unc-104HMC03512 has partially lethal - majority die phenotype
Argk1HMS02262, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority live phenotype
Apc2GD11854, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, bowlJF02419, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, bnlHMS01046, brmGD4507 has partially lethal - majority die phenotype
Scer\GAL4repo.PU, aHMC03685, brmGD4507 has partially lethal - majority live phenotype
Scer\GAL4repo.PU, acHMC03406, brmGD4507 has partially lethal - majority die phenotype
CG3662GLC01437, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority live phenotype
Scer\GAL4repo.PU, aopJF02323, brmGD4507 has partially lethal - majority die phenotype
BicCHMS01407, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
AgpsHMS01339, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority live phenotype
AhcyL1GD14332, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority die phenotype
CG10348HMS02808, Scer\GAL4repo.PU, brmGD4507 has partially lethal - majority live phenotype
Hex-AGL00023, Scer\GAL4repo.PU, brmGD4507 has partially lethal phenotype
Scer\GAL4nub.PK, brmGD4507 has wing blade phenotype, enhanceable by httint
Scer\GAL4en.PU, brmGD4507 has wing blade phenotype, enhanceable by httint
Scer\GAL4Tub.PU, brmGD4507, hpoBF33 has midgut | somatic clone phenotype
The wing defects induced by expression of brmGD4507 under the control of either Scer\GAL4nub.PK or Scer\GAL4en.PU are enhanced by combination with httint.
Expression of brmGD4507 greatly suppresses the intestinal stem cell overproliferation and hyperplasia seen when ykiScer\UAS.cZa is expressed in adult flies under the control of Scer\GAL4esg-NP5130.
Expression of brmGD4507 greatly suppresses the intestinal stem cell overproliferation seen when sdGA.Scer\UAS.T:Scer\GAL4-GAD.T:Ivir\HA1 is expressed in adult flies under the control of Scer\GAL4esg-NP5130.
Expression of brmGD4507 under the control of Scer\GAL4tub.PU reduces the growth of hpoBF33 mutant midgut clones.