FlyBase Allele Report: Dmel\Hex-A[GL00023]

General Information

Symbol

Dmel\Hex-A^GL00023

Species

D. melanogaster

Name

FlyBase ID

FBal0262514

Feature type

allele

Associated gene

Dmel\Hex-A

Associated Insertion(s)

Carried in Construct

P{TRiP.GL00023}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.GL00023}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-GL00023

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neurophysiology, with Scer\GAL4^elav-C155

(Mallik et al., 2025)

decreased size | adult stage, with Scer\GAL4^C-765

(Spannl et al., 2020)

Phenotype Manifest In

presynaptic active zone, with Scer\GAL4^elav-C155

(Mallik et al., 2025)

wing, with Scer\GAL4^C-765

(Spannl et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Hex-A^GL00023/Hex-C^HMC04708, Scer\GAL4^elav-C155 is a non-enhancer of abnormal neurophysiology phenotype of ND-20L^HMJ23777, ND-20^HMJ23777, Scer\GAL4^elav-C155

(Mallik et al., 2025)

Suppressor of

Statement

Reference

Hex-A^GL00023, Scer\GAL4^elav-C155 is a suppressor of abnormal neurophysiology phenotype of ND-20L^HMJ23777, ND-20^HMJ23777, Scer\GAL4^elav-C155

(Mallik et al., 2025)

Hex-A^GL00023, Scer\GAL4^repo.PU is a suppressor | partially of lethal - all die during P-stage phenotype of Scer\GAL4^repo.PU, brm^GD4507

(Tegeder et al., 2019)

NOT Suppressor of

Statement

Reference

Hex-A^GL00023/Hex-C^HMC04708, Scer\GAL4^elav-C155 is a non-suppressor of abnormal neurophysiology phenotype of ND-20L^HMJ23777, ND-20^HMJ23777, Scer\GAL4^elav-C155

(Mallik et al., 2025)

Other

Statement

Reference

Hex-A^GL00023, Hex-C^HMC04708, Scer\GAL4^elav-C155 has abnormal neurophysiology phenotype

(Mallik et al., 2025)

Hex-A^GL00023, Scer\GAL4^repo.PU, brm^GD4507 has partially lethal phenotype

(Tegeder et al., 2019)

Phenotype Manifest In

Enhancer of

Statement

Reference

Hex-A^GL00023, Scer\GAL4^drm.7.1 is an enhancer of terminal tracheal cell | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)

Suppressor of

Statement

Reference

Hex-A^GL00023/Hex-C^HMC04708, Scer\GAL4^elav-C155 is a suppressor | partially of presynaptic active zone phenotype of ND-20L^HMJ23777, ND-20^HMJ23777, Scer\GAL4^elav-C155

(Mallik et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

35155

y¹ sc^* v¹ sev²¹; P{TRiP.GL00023}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Hex-A^GL00023

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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