FlyBase Allele Report: Dmel\dve[KK115422]

General Information

Symbol

Dmel\dve^KK115422

Species

D. melanogaster

Name

FlyBase ID

FBal0260005

Feature type

allele

Associated gene

Dmel\dve

Associated Insertion(s)

Carried in Construct

P{KK115422}

Also Known As

UAS-dve-IR, UAS-dveRNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK115422}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK115422

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal mating behavior | female, with Scer\GAL4^dve.13, dve⁰¹⁷³⁸

(Minami et al., 2012)

Phenotype Manifest In

male accessory gland, with Scer\GAL4^dve.13, dve⁰¹⁷³⁸

(Minami et al., 2012)

Detailed Description

Statement

Reference

The ratio of the cross-section areas of the accessory gland/ejaculatory bulb is significantly reduced compared to wild type in males expressing dve^KK115422 under the control of Scer\GAL4^dve.13 in a dve⁰¹⁷³⁸/+ background. Binucleation of main type cells is relatively normal in the mutant accessory glands.

The number of eggs laid per day by females mated to males expressing dve^KK115422 under the control of Scer\GAL4^dve.13 in a dve⁰¹⁷³⁸/+ background is reduced and these females show high re-mating activity (comparable to those of virgin female controls) at 48 hours after the first mating.

(Minami et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

dve^KK115422/Scer\GAL4^{αTub84B.Switch.PK} is a suppressor of abnormal heat stress response | male limited | RU486 conditional phenotype of Scer\GAL4^{αTub84B.Switch.PK}, Trap1^UAS.cBa

(Baqri et al., 2014)

Other

Statement

Reference

Scer\GAL4^hh.PU, dve^KK115422, nab^GD1607 has visible phenotype

(Perea et al., 2013)

Phenotype Manifest In

Other

Statement

Reference

Scer\GAL4^hh.PU, dve^KK115422, nab^GD1607 has wing disc posterior compartment phenotype

(Perea et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of both nab^GD1607 and dve^KK115422 under the control of Scer\GAL4^hh.PU results in a strong reduction in the size of the posterior compartment of the wing.

(Perea et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

dve⁰¹⁷³⁸, dve^KK115422, Scer\GAL4^ey.PH rescues dve^A.UAS

(Puli et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v109538

P{KK115422}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

dve^KK115422

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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