FlyBase Allele Report: Dmel\Rab21[KK115582]

General Information

Symbol

Dmel\Rab21^KK115582

Species

D. melanogaster

Name

FlyBase ID

FBal0260068

Feature type

allele

Associated gene

Dmel\Rab21

Associated Insertion(s)

Carried in Construct

P{KK115582}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK115582}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK115582

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | adult stage, with Scer\GAL4^NP0001

(Nassari et al., 2022)

increased cell death | adult stage, with Scer\GAL4^NP0001

(Nassari et al., 2022)

increased occurrence of cell division | adult stage, with Scer\GAL4^NP0001

(Nassari et al., 2022)

short lived, with Scer\GAL4^NP0001

(Nassari et al., 2022)

Phenotype Manifest In

adult enteroendocrine cell | increased number, with Scer\GAL4^NP0001

(Nassari et al., 2022)

adult gut, with Scer\GAL4^NP0001

(Nassari et al., 2022)

fat body, with Scer\GAL4^NP0001

(Nassari et al., 2022)

intestinal stem cell | adult stage | increased number, with Scer\GAL4^NP0001

(Nassari et al., 2022)

lipid droplet | adult stage, with Scer\GAL4^NP0001

(Nassari et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Rab21^KK115582, Scer\GAL4^NP0001 has increased occurrence of cell division | adult stage phenotype, suppressible by yki^HMS00041, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has increased cell death | adult stage phenotype, suppressible by yki^HMS00041, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has increased occurrence of cell division | adult stage phenotype, suppressible by Egfr^DN.UAS.cBa, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has increased occurrence of cell division | adult stage phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has increased occurrence of cell division | adult stage phenotype, suppressible by upd3^HMS00646, Scer\GAL4^NP0001

(Nassari et al., 2022)

NOT suppressed by

Statement

Reference

Rab21^KK115582, Scer\GAL4^NP0001 has increased occurrence of cell division | adult stage phenotype, non-suppressible by Rab11^{Q70L.UASp.YFP}, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has increased occurrence of cell division | adult stage phenotype, non-suppressible by apolpp^HM05157, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has increased occurrence of cell division | adult stage phenotype, non-suppressible by Tret1^HMS02573, Scer\GAL4^NP0001

(Nassari et al., 2022)

Phenotype Manifest In

Suppressed by

Statement

Reference

Rab21^KK115582, Scer\GAL4^NP0001 has adult gut phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has adult gut phenotype, suppressible by upd3^HMS00646, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has adult gut phenotype, suppressible by yki^HMS00041, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has adult gut phenotype, suppressible by Egfr^DN.UAS.cBa, Scer\GAL4^NP0001

(Nassari et al., 2022)

NOT suppressed by

Statement

Reference

Rab21^KK115582, Scer\GAL4^NP0001 has adult gut phenotype, non-suppressible by Rab11^{Q70L.UASp.YFP}, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has adult gut phenotype, non-suppressible by Tret1^HMS02573, Scer\GAL4^NP0001

(Nassari et al., 2022)

Rab21^KK115582, Scer\GAL4^NP0001 has adult gut phenotype, non-suppressible by apolpp^HM05157, Scer\GAL4^NP0001

(Nassari et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Rab21^KK115582 is rescued by Rab21^UAS.RR/Scer\GAL4^NP0001

(Nassari et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v109991

P{KK115582}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Rab21^KK115582

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections