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General Information
Symbol
Dmel\chas1
Species
D. melanogaster
Name
FlyBase ID
FBal0260706
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Comment:

Deletion that includes the 5' untranslated regions and 5' coding exons of all chas isoforms.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Recombination between the two progenitor insertions has deleted the sequence between them, removing part of the chas gene.

Deletion that includes the 5' untranslated regions and start codons of both chas isoforms.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutant flies have anterior indentations in the notum epidermis.

Mutants show planar polarity defects in the notum.

Homozygous clones in the notum nonautonomously influence the polarity of neighbouring bristles and trichomes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

chas1 has visible phenotype, enhanceable by dpyov1

chas1 has abnormal planar polarity phenotype, enhanceable by jbugBG00406/jbug[+]

Suppressed by
Statement
Reference
Enhancer of
Statement
Reference

chas1 is an enhancer of visible phenotype of dpyov1

Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

chas1 has mesothoracic tergum phenotype, enhanceable by dpyov1

Suppressed by
Statement
Reference

chas1 has chaeta phenotype, suppressible by NICN.UAS/Scer\GAL41151

Enhancer of
Statement
Reference

chas1 is an enhancer of mesothoracic tergum phenotype of dpyov1

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

chas1 dpov1 double mutants show enhanced indentations of the anterior notum epidermis and enhanced planar polarity defects compared to either single mutant.

jbugBG00406/+ enhances the planar polarity defects seen in the notum of chas1 mutants.

chas1 ; fz21 double mutants show a novel phenotype, with bristles on the notum oriented towards the anterior.

Expression of NICN.Scer\UAS under the control of Scer\GAL41151 suppresses the planar polarity defects seen in the notum of chas1 flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (2)