FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\TER94UAS.cRa
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General Information
Symbol
Dmel\TER94UAS.cRa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Ritson
FlyBase ID
FBal0261042
Feature type
allele
Associated gene
Dmel\TER94
Associated Insertion(s)
Carried in Construct
P{UAS-TER94.R}
Also Known As
UAS-VCP, UAS-dVCP wt
Key Links
Transgenic product class
wild_type
(Ritson et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ritson et al., 2010)
Mutagen
in vitro construct
(Ritson et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-TER94.R}
Cytology
Description

UAS regulatory sequences drive expression of TER94 coding sequences.

(Ritson et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
TER94
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of TER94Scer\UAS.cRa under the control of Scer\GAL4VGlut-OK371 has no effect on viability. Locomotor behaviour is normal and no defects are seen in neuromuscular junction morphology in third instar larvae.

      (Kim et al., 2013)

      Expression of TER94Scer\UAS.cRa under the control of Scer\GAL4ey.PH or Scer\GAL4GMR.PF does not have any strong adult eye phenotype.

      (O'Sullivan et al., 2013)

      Expression of TER94Scer\UAS.cRa in the developing eye under the control of Scer\GAL4GMR.PF generates a mild rough eye phenotype but the flies still have a highly organised ommatidial array.

      (Ritson et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      NOT Enhanced by
      NOT suppressed by
      Enhancer of
      NOT Enhancer of
      Suppressor of
      NOT Suppressor of
      Phenotype Manifest In
      Enhanced by
      NOT Enhanced by
      NOT suppressed by
      Enhancer of
      NOT Enhancer of
      Suppressor of
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of TER94Scer\UAS.cRa under the control of Scer\GAL4EDTP-DJ694 partially suppresses the thorax indentation phenotype and climbing defects seen in Pink1B9 adults.

      The mitochondrial defects seen in the flight muscles of Pink1B9 adults are suppressed by expression of TER94Scer\UAS.cRa under the control of Scer\GAL4EDTP-DJ694.

      Expression of TER94Scer\UAS.cRa under the control of Scer\GAL4EDTP-DJ694 enhances the thorax indentation phenotype seen in park25 adults, but has no significant effect on the climbing defect seen in these animals.

      (Kim et al., 2013)

      The adult eye phenotype (small or rough eyes) characteristic for flies expressing atlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF or Scer\GAL4ey.PH is exacerbated further by co-expression of TER94Scer\UAS.cRa.

      (O'Sullivan et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of TER94Scer\UAS.cRa and Hsap\TARDBPScer\UAS.cRa or Hsap\TARDBPmutNES.Scer\UAS in the developing eye under the control of Scer\GAL4GMR.PF doesn't generate an eye phenotype, indicating there is no interaction between these transgenes.

      Co-expression of TER94Scer\UAS.cRa with Hsap\TARDBPmutNLS.Scer\UAS in the developing eye, under the control of Scer\GAL4GMR.PF, resulting in a range of phenotypes, from a mild enhancement of the rough eye phenotype to lethality.

      The eye degeneration phenotype found upon expression of TER94R152H.Scer\UAS under the control of Scer\GAL4GMR.PF is strongly enhanced by co-expression of Hsap\TARDBPM337V.Scer\UAS.

      (Ritson et al., 2010)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      TER94Scer\UAS.cRa
      TER94UAS.cRa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Ritson
      Secondary FlyBase IDs
        References (12)