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General Information
Symbol
Dmel\NdfipUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0261132
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of Ndfip which is tagged with a Tag:HA epitope.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Over-expression of a single copy of NdfipScer\UAS.T:Ivir\HA1 with Scer\GAL4ptc-559.1 or Scer\GAL4Bx-MS1096 has minimal effects on the adult wing. However, over-expression of two copies of NdfipScer\UAS.T:Ivir\HA1 using Scer\GAL4Bx-MS1096 results in severe wing disruption, with increased bristles present at the wing margin.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of NdfipScer\UAS.T:Ivir\HA1 enhances the Nedd4GS13178, Scer\GAL4ptc-559.1 wing phenotype, with severe loss of the wing margin producing smaller wings.

Co-expression of NdfipScer\UAS.T:Ivir\HA1 enhances the Su(dx)Scer\UAS.cCa, Scer\GAL4ptc-559.1 wing phenotype, with loss of the wing margin.

Co-expression of NdfipScer\UAS.T:Ivir\HA1 enhances the Nedd4GS13178, Scer\GAL4Bx-MS1096 wing phenotype, with little intervein space evident, thick veins and smaller wings.

Co-expression of NdfipScer\UAS.T:Ivir\HA1 enhances the Su(dx)Scer\UAS.cCa, Scer\GAL4Bx-MS1096 wing phenotype, resulting in a severely disrupted wing with increased vein thickening and smaller wing size.

Wings discs that co-express Su(dx)Scer\UAS.cCa and NdfipScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Bx-MS1096 are undulated, unlike wild type.

Wings discs that co-express Nedd4GS13178 and NdfipScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Bx-MS1096 are quite undulated and wrinkled, unlike wild type.

Scer\GAL4Bx-MS1096-mediated expression of NdfipScer\UAS.T:Ivir\HA1 suppresses the N264-39/+ wing phenotypes.

Coexpression of NdfipScer\UAS.T:Ivir\HA1 suppresses the Scer\GAL4Bx-MS1096, dxGD1427 wing phenotype, reducing the vein thickening.

The Ser1/+ wing phenotype is suppressed by Scer\GAL4Bx-MS1096-mediated overexpression of NdfipScer\UAS.T:Ivir\HA1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
NdfipScer\UAS.T:Ivir\HA1
NdfipUAS.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (1)