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General Information
Symbol
Dmel\lokGL00020
Species
D. melanogaster
Name
FlyBase ID
FBal0262511
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of lokGL00020 under the control of Scer\GAL4nos.PU in the absence of DNA damage does not affect the number of germline stem cells in adult female germaria.

Females heterozygous for lokGL00020 and MTD-Gal4 (consists of Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16) crossed to lokGL00020 males results in: 3% hatching; egg/embryonic phenotype: "empty, all white"; maternal effect.

The expression of lokGL00020 under the control of Scer\GAL4elav.PU induces an increase in lifespan compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

lokGL00020/Scer\GAL4nos.PU is a suppressor of decreased cell number | female | adult stage | temperature conditional phenotype of Crei\I-CreIhs.PR

Phenotype Manifest In
Suppressor of
Statement
Reference

lokGL00020/Scer\GAL4nos.PU is a suppressor of female germline stem cell | adult stage | temperature conditional phenotype of Crei\I-CreIhs.PR

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

The loss of germline stem cells (GSCs) observed upon heat-shock induced expression of Crei\I-CreIhs.PR (to introduce DNA damage) is suppressible by Scer\GAL4nos.PU-driven expression of lokGL00020.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
lokGL00020
Name Synonyms
Secondary FlyBase IDs
    References (6)