FlyBase Allele Report: Dmel\aux[GL00213]

General Information

Symbol

Dmel\aux^GL00213

Species

D. melanogaster

Name

FlyBase ID

FBal0262685

Feature type

allele

Associated gene

Dmel\aux

Associated Insertion(s)

Carried in Construct

P{TRiP.GL00213}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.GL00213}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-GL00213

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates Parkinson's disease 1

modeled by Hsap\SNCA^QUAS.cOa

(Olsen and Feany, 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult posterior midgut epithelium, with Scer\GAL4^{Delta-05151-G}

(Zhao et al., 2022)

adult posterior midgut epithelium, with Scer\GAL4^NP5130

(Zhao et al., 2022)

adult posterior midgut epithelium, with Scer\GAL4^{Su(H).GBE.cLa}

(Zhao et al., 2022)

adult posterior midgut epithelium | somatic clone, with Scer\GAL4^Act.PU

(Zhao et al., 2022)

enteroblast of posterior adult midgut epithelium | increased number, with Scer\GAL4^NP5130

(Zhao et al., 2022)

enteroblast of posterior adult midgut epithelium | increased number, with Scer\GAL4^{Su(H).GBE.cLa}

(Zhao et al., 2022)

enterocyte of posterior adult midgut epithelium | increased number, with Scer\GAL4^Act.PU

(Zhao et al., 2022)

enterocyte of posterior adult midgut epithelium | increased number, with Scer\GAL4^NP5130

(Zhao et al., 2022)

intestinal stem cell of posterior adult midgut epithelium | increased number, with Scer\GAL4^{Delta-05151-G}

(Zhao et al., 2022)

intestinal stem cell of posterior adult midgut epithelium | increased number, with Scer\GAL4^NP5130

(Zhao et al., 2022)

intestinal stem cell of posterior adult midgut epithelium | increased number | somatic clone, with Scer\GAL4^Act.PU

(Zhao et al., 2022)

Detailed Description

Statement

Reference

Females heterozygous for aux^GL00213 and MTD-Gal4 (consists of Scer\GAL4^{otu.T:Hsim\VP16}, Scer\GAL4^nos.PG and Scer\GAL4^{nos.UTR.T:Hsim\VP16}) crossed to aux^GL00213 males results in: "few eggs,0% hatching"; egg/embryonic phenotype: few eggs; oogenesis defect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions