FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Pdcd4BG00495
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General Information
Symbol
Dmel\Pdcd4BG00495
Species
D. melanogaster
Name
FlyBase ID
FBal0265199
Feature type
allele
Associated gene
Dmel\Pdcd4
Associated Insertion(s)
P{GT1}Pdcd4BG00495
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Magwire et al., 2010)
Progenitor genotype
Associated Insertion(s)
P{GT1}Pdcd4BG00495
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GT1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Male and female CG10990BG00495 mutants show an increased lifespan compared to controls.

      Starvation response is unaffected in 1 week and 6 week male flies. Females show increased resistance at 1 week, but resistance is reduced compared to controls at 6 weeks.

      Chill coma recovery time in both males and females is similar to controls at one week, but recovery time is improved compared to controls in both sexes at 6 weeks.

      No change in climbing ability is seen in either males or females at 1 week but improved fitness compared to controls is seen at 6 weeks in both sexes.

      (Magwire et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      CG10990BG00495 BG00004BG00004 double heterozygous males have a long lifespan compared to controls.

      CG10990BG00495 crolBG00346 double heterozygous males have a long lifespan compared to controls.

      CG10990BG00495 BG00761BG00761 double heterozygous females have a long lifespan compared to controls.

      (Magwire et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CG10990BG00495
      Pdcd4BG00495
      Name Synonyms
      Secondary FlyBase IDs
        References (1)