FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hiwΔN.UAS.Tag:TAP
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General Information
Symbol
Dmel\hiwΔN.UAS.Tag:TAP
Species
D. melanogaster
Name
FlyBase ID
FBal0265666
Feature type
allele
Associated gene
Dmel\hiw
Associated Insertion(s)
Carried in Construct
P{UAS-NTAP-hiw.ΔN}
Key Links
Transgenic product class
inframe_deletion
(Tian et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Tian et al., 2011)
Mutagen
in vitro construct
(Tian et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-NTAP-hiw.ΔN}
Cytology
Description

UAS regulatory sequences drive expression of hiw C-terminal sequences, starting at residue 2420 and tagged at the N-terminal with Tag:TAP.

(Tian et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
hiw
Tagged with
Tag:TAP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of hiwΔN.Scer\UAS.T:Zzzz\TAP under the control of Scer\GAL4elav.Switch.PO significantly increases the number of boutons at muscle 4 neuromuscular junctions (although not as much as in a hiwND8 heterozygous background).

      Expression of hiwΔN.Scer\UAS.T:Zzzz\TAP presynaptically in hiwND8 heterozygotes, under the control of Scer\GAL4elav.Switch.PO results in notable synaptic terminal overgrowth.

      (Tian et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Rae1Scer\UAS.T:Avic\GFP-EGFP completely suppresses the synaptic overgrowth phenotypes seen upon expression of hiwΔN.Scer\UAS.T:Zzzz\TAP under the control of Scer\GAL4BG380.

      (Tian et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4elav-C155/hiwΔN.UAS.Tag:TAP fails to rescue hiwND8

      (Tian et al., 2011)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      hiwΔN.Scer\UAS.T:Zzzz\TAP
      hiwΔN.UAS.Tag:TAP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)