FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Xbp1HMS03015
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General Information
Symbol
Dmel\Xbp1HMS03015
Species
D. melanogaster
Name
FlyBase ID
FBal0266587
Feature type
allele
Associated gene
Dmel\Xbp1
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS03015}
Also Known As
xbp1 RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
in vitro construct
(Ni et al., 2011.7.19)
Progenitor genotype
Carried in construct
P{TRiP.HMS03015}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMS03015
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The temporally regulated expression (by Gal80[ts]) of Xbp1HMS03015, for 5 days under the control of Scer\GAL4NP0001, or for 6 days under the control of Scer\GAL4Su(H).GBE or under the combined control of Scer\GAL4NP5130 and Scer\GAL80Su(H).GBE, leads to a strong increase in the proportion of mitotic cells in the adults midgut, as compared to controls.

      (Wang et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      NOT suppressed by
      NOT Enhancer of
      Statement
      Reference

      Scer\GAL4hh-Gal4/Xbp1HMS03015 is a non-enhancer of neoplasia | larval stage phenotype of Alg3tid2/Alg3tid1

      (de Vreede et al., 2018)
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4hh-Gal4/Xbp1HMS03015 is a non-suppressor of neoplasia | larval stage phenotype of Alg3tid2/Alg3tid1

      (de Vreede et al., 2018)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Xbp1HMS03015
      Xbp1RNAiHMS03015
      (Wang et al., 2015)
      xbp1RNAi-1
      (Zhao et al., 2023)
      Name Synonyms
      Secondary FlyBase IDs
        References (15)