FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\painp60.UAS.Venus
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General Information
Symbol
Dmel\painp60.UAS.Venus
Species
D. melanogaster
Name
FlyBase ID
FBal0267055
Feature type
allele
Associated gene
Dmel\pain
Associated Insertion(s)
Carried in Construct
P{UAS-painp60::VFP}
Key Links
Transgenic product class
wild_type
(Hwang et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hwang et al., 2012)
Mutagen
in vitro construct
(Hwang et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-painp60::VFP}
Cytology
Description

UAS regulatory sequences drive expression of a pain[p60] isoform (encoding an 83 amino acid residue protein containing an intracellular amino terminal domain) tagged at the C-terminus with Venus.

(Hwang et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
pain
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4NP7022, painp60.UAS.Venus, Scer\GAL4pain-GAL4 rescues painNP7022/painGAL4

      (Hwang et al., 2012)
      Fails to rescue

      Scer\GAL4NP7022, painp60.UAS.Venus, Scer\GAL4pain-GAL4 fails to rescue painNP7022/painGAL4

      (Hwang et al., 2012)
      Comments

      Expression of painp60.Scer\UAS.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4pain-GAL4 and Scer\GAL4NP7022 does not rescue nociception responses to a 46[o]C thermal stimulus in painGAL4/painNP7022 trans-heterozygotes but does improve the mechanical nociception responses of the mutant animals, such that they are no longer different from wild-type.

      (Hwang et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      painp60.Scer\UAS.T:Avic\GFP-YFP.Venus
      painp60.UAS.Venus
      Name Synonyms
      Secondary FlyBase IDs
        References (1)