FlyBase Allele Report: Dmel\shi[7C7]

General Information

Symbol

Dmel\shi^7C7

Species

D. melanogaster

Name

FlyBase ID

FBal0267316

Feature type

allele

Associated gene

Dmel\shi

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Legent et al., 2012)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | somatic clone

(Legent et al., 2012)

Phenotype Manifest In

eye | somatic clone

(Legent et al., 2012)

eye disc | somatic clone

(Legent et al., 2015)

eye disc | somatic clone | third instar larval stage

(Legent et al., 2012)

photoreceptor | somatic clone | increased number | third instar larval stage

(Legent et al., 2015)

Detailed Description

Statement

Reference

shi^7C7 mutant eye disc clones differentiate excessive photoreceptors.

(Legent et al., 2015)

Nearly all cells posterior the morphogenetic furrow differentiate as photoreceptors in clones in the third larval instar eye disc.

(Legent et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

shi^7C7 has photoreceptor | increased number | somatic clone | third instar larval stage phenotype, suppressible by Vps4^3B1

(Legent et al., 2015)

NOT suppressed by

Statement

Reference

shi^7C7 has eye disc | somatic clone phenotype, non-suppressible by Hrs^D28

(Legent et al., 2015)

shi^7C7 has photoreceptor | increased number | somatic clone | third instar larval stage phenotype, non-suppressible by Hrs^D28

(Legent et al., 2015)

NOT Suppressor of

Statement

Reference

shi^7C7 is a non-suppressor of eye disc | somatic clone | third instar larval stage phenotype of Vps4^3B1

(Legent et al., 2015)

shi^7C7 is a non-suppressor of photoreceptor | somatic clone | third instar larval stage phenotype of Vps4^3B1

(Legent et al., 2015)

shi^7C7/Dronc^I29 is a non-suppressor of eye disc | somatic clone | third instar larval stage phenotype of Vps4^3B1

(Legent et al., 2015)

shi^7C7/Dronc^I29 is a non-suppressor of photoreceptor | somatic clone | third instar larval stage phenotype of Vps4^3B1

(Legent et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Hrs^D28 does not suppress the increased photoreceptor differentiation seen in shi^7C7 mutant eye disc clones.

Vps4^3B1 suppresses the increase in photoreceptor number seen in shi^7C7 mutant eye disc clones, with the double mutants showing the photoreceptor loss seen in Vps4^3B1 mutants alone. The same is seen in a Dronc^I29 mutant background.

(Legent et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

shi^7C7

(Courgeon et al., 2018, Legent et al., 2015, Legent et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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