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General Information
Symbol
Dmel\gogoDDD.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0267395
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a mutant form of gogo in which the YYD motif in the C2 cytoplasmic domain has been mutated to DDD.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of gogoDDD.Scer\UAS under the control of Scer\GAL4GMR.PF results in premature stopping of R8 axons at the M1 medulla layer. Targeting of R7 neurons is normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
NOT Enhanced by
NOT suppressed by
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of stanScer\UAS.cUa and gogoFFD.Scer\UAS under the control of Scer\GAL4GMR.PF does not induce mistargeting of R7 photoreceptor cells to the R8 recipient layer (M3).

Expression of InRK1409A.Scer\UAS does not affect the R8 axon stopping phenotype seen when gogoDDD.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF.

Expression of InRScer\UAS.cHa slightly enhances the R8 axon stopping phenotype seen when gogoDDD.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
gogoDDD.Scer\UAS
gogoDDD.UAS
Name Synonyms
Secondary FlyBase IDs
    References (1)