FlyBase Allele Report: Dmel\Ptp61F[RNAi.UAS.WIZ]

General Information

Symbol

Dmel\Ptp61F^RNAi.UAS.WIZ

Species

D. melanogaster

Name

FlyBase ID

FBal0269408

Feature type

allele

Associated gene

Dmel\Ptp61F

Associated Insertion(s)

Carried in Construct

P{UAS-Ptp61F.RNAi.WIZ}

Key Links

Transgenic product class

RNAi_reagent

(Ku et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ku et al., 2009)

Mutagen

in vitro construct

(Ku et al., 2009)

Progenitor genotype

Carried in construct

P{UAS-Ptp61F.RNAi.WIZ}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat corresponding to +901 to +1415 of the Ptp61F coding sequence.

(Ku et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Ptp61F

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Ptp61F^RNAi.UAS.WIZ/Scer\GAL4^GMR.PU is an enhancer of abnormal size phenotype of InR^A1325D.GMR

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU is an enhancer of visible phenotype of Hem^{UAS.Tag:Myr(Src64B)}, Scer\GAL4^GMR.PU

(Ku et al., 2009)

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU is an enhancer of visible phenotype of Abl^UAS.cFa, Scer\GAL4^GMR.PU

(Ku et al., 2009)

Suppressor of

Statement

Reference

Ptp61F^RNAi.UAS.WIZ/Scer\GAL4^GMR.PU is a suppressor of abnormal size | dominant phenotype of Egfr^E1

(Tchankouo-Nguetcheu et al., 2014)

Other

Statement

Reference

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU, rl^Sem has abnormal size phenotype

(Tchankouo-Nguetcheu et al., 2014)

Phenotype Manifest In

Enhancer of

Statement

Reference

Ptp61F^RNAi.UAS.WIZ/Scer\GAL4^GMR.PU is an enhancer of eye phenotype of InR^A1325D.GMR

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F^RNAi.UAS.WIZ/Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Ras85D^V12.sev

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F^RNAi.UAS.WIZ/Scer\GAL4^GMR.PU is an enhancer of wing vein phenotype of rl^Sem

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F^RNAi.UAS.WIZ/Scer\GAL4^GMR.PU is an enhancer of wing vein | ectopic phenotype of rl^Sem

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hem^{UAS.Tag:Myr(Src64B)}, Scer\GAL4^GMR.PU

(Ku et al., 2009)

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU is an enhancer of filamentous actin | pupal stage phenotype of Hem^{UAS.Tag:Myr(Src64B)}, Scer\GAL4^GMR.PU

(Ku et al., 2009)

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Abl^UAS.cFa, Scer\GAL4^GMR.PU

(Ku et al., 2009)

NOT Enhancer of

Statement

Reference

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PU, pnt^P2.VP16.UAS

(Tchankouo-Nguetcheu et al., 2014)

Suppressor of

Statement

Reference

Ptp61F^RNAi.UAS.WIZ/Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Egfr^E1

(Tchankouo-Nguetcheu et al., 2014)

NOT Suppressor of

Statement

Reference

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PU, pnt^P2.VP16.UAS

(Tchankouo-Nguetcheu et al., 2014)

Other

Statement

Reference

Ptp61F^RNAi.UAS.WIZ, Scer\GAL4^GMR.PU, rl^Sem has eye phenotype

(Tchankouo-Nguetcheu et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

rl^Sem in combination with Scer\GAL4^GMR.PU-driven Ptp61F^{dsRNA.Scer\UAS.WIZ} results in larger than normal eyes.

(Tchankouo-Nguetcheu et al., 2014)

The rough eye phenotype caused by expression of Hem^{Scer\UAS.T:Myr-Src64B} under the control of Scer\GAL4^GMR.PU is enhanced by co-expression of Ptp61F^{dsRNA.Scer\UAS.WIZ}.

The defects seen in F-actin organisation in 40 hour pupal eye discs of animals expressing Hem^{Scer\UAS.T:Myr-Src64B} under the control of Scer\GAL4^GMR.PU are increased significantly by co-expression of Ptp61F^{dsRNA.Scer\UAS.WIZ}.

The rough eye phenotype caused by expression of Abl^Scer\UAS.cFa under the control of Scer\GAL4^GMR.PU is enhanced by co-expression of Ptp61F^{dsRNA.Scer\UAS.WIZ}.

(Ku et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

56510

w^*; P{UAS-Ptp61F.RNAi.WIZ}i2-5

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ptp61F^RNAi.UAS.WIZ

Ptp61F^{dsRNA.Scer\UAS.WIZ}

Ptp61F^{dsRNA.UAS.WIZ}

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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