FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4GSG2850
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General Information
Symbol
Scer\GAL4GSG2850
Species
S. cerevisiae
Name
FlyBase ID
FBal0269601
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{Switch2}GSG2850
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{Switch2}GSG2850
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{Switch2}
    Encoded product / tool
    GAL4::GS
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        third instar larval stage
        thoracic neuron | subset
        (Nicholson et al., 2008)
        neuron | subset of larval ventral nerve cord
        (Nicholson et al., 2008)
        larval A1-7-innervating RP2 motor neuron
        (Nicholson et al., 2008)
        VL fascicle
        (Nicholson et al., 2008)
        neuron | subset of larval brain
        (Nicholson et al., 2008)
        embryonic/larval neuromuscular junction
        (Nicholson et al., 2008)
        chordotonal organ
        (Nicholson et al., 2008)
        larval tracheal innervating neuron
        (Nicholson et al., 2008)
        ring gland
        (Nicholson et al., 2008)
        embryonic/larval oenocyte
        (Nicholson et al., 2008)
        Additional Information
        Statement
        Reference

        ScerGAL4GSG2850 drives mifepristone-inducible expression primarily in neurons. In the ventral nerve cord, strong expression is observed in a single paired thoracic neuron; moderate to weak expression is observed in 1-4 cells/hemisegment, including the A1-7 dorsal motor neurons (MNISN-Is); in 20+ lateral cells/hemisegment; and in scattered ventral cells. The expression pattern is stronger in the anterior ventral nerve cord. Expression is observed in longitudinal intersegmental processes in the Fas2-positive VL fascicles. Moderate expression is observed in cells throughout the brain hemispheres. Moderate expression is observed in a subset of chordotonal organs, and in tracheal innervating neurons (md-td). Variable expression is observed in type I neuromuscular junctions. Expression is observed in oenocytes and in the ring gland. Very faint uninduced expression is observed at the dorsal CNS midine.

        (Nicholson et al., 2008)
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4GSG2850
        Name Synonyms
        Secondary FlyBase IDs
          References (1)