FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\psidin85D1
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General Information
Symbol
Dmel\psidin85D1
Species
D. melanogaster
Name
FlyBase ID
FBal0277249
Feature type
allele
Associated gene
Dmel\psidin
Associated Insertion(s)
Carried in Construct
Also Known As
psid85D1
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Kim et al., 2011)
Progenitor genotype
Cytology
Description

Amino acid replacement: W807term.

(Kim et al., 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:20,025,620..20,025,620 [+]
Nucleotide change:

G20025620A

Amino acid change:

W807term | psidin-PA

Reported amino acid change:

W807term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Kim et al., 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  cancer
      modeled by Rbf15aΔ
      (Sheng and Du, 2020)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous border cells show defects in migration: some of the mutant cells show no migration at all, and 25% of mutant clusters fail to reach the oocyte by stage 10.

      (Kim et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      psidin85D1/psidin[+], tsr1/tsrntf has lethal phenotype

      (Kim et al., 2011)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Rbf15aΔ/Rbf15aΔ is synthetic lethal with psidin85D1/psidin85D1, as double mutant clones are not or rarely found in the eye; as consequence, eyes are smaller. Both phenotypes are exacerbated in a Minute background.

      (Sheng and Du, 2020)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      psid-D1
      (Sheng and Du, 2020)
      psid85D1
      (Sheng and Du, 2020, Kim et al., 2011)
      psidin85D1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)