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General Information
Symbol
Dmel\Vps26HMS01769
Species
D. melanogaster
Name
FlyBase ID
FBal0278887
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Vps26-RNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing Vps26HMS01769 under the control of either Scer\GAL4insc-Mz1407 or Scer\GAL4pnt-14-94 results in supernumerary neuroblasts in the larval brain; the same can also be observed upon Scer\GAL4GMR9D11-driven expression, depending on the Scer\GAL4GMR9D11 insertion.

Expression of Vps26HMS01769 driven by Scer\GAL4GMR.PU causes an eye phenotype with presence of black lesions (in around 36% of mutant flies, compared to 3% in controls).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Co-expression of Hsap\LRRK2I2020T.Scer\UAS does not significantly enhance eye phenotypes (presence of black lesions) in flies with expression of Vps26HMS01769 driven by Scer\GAL4GMR.PU.

Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Vps26HMS01769
Name Synonyms
Secondary FlyBase IDs
    References (5)