FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pdm3UAS.CFP
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General Information
Symbol
Dmel\pdm3UAS.CFP
Species
D. melanogaster
Name
FlyBase ID
FBal0279838
Feature type
allele
Associated gene
Dmel\pdm3
Associated Insertion(s)
Carried in Construct
P{UAS-pdm3.CFP}
Key Links
Transgenic product class
wild_type
(Chen et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Chen et al., 2012)
Mutagen
in vitro construct
(Chen et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-pdm3.CFP}
Cytology
Description

UAS regulatory sequences drive expression of pdm3 coding sequences tagged at the carboxy-terminal end with CFP.

(Chen et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
pdm3
Tagged with
CFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of pdm3Scer\UAS.T:Avic\GFP-CFP in R neurons, under the control of Scer\GAL4c105, Scer\GAL4lilli-189Y, or Scer\GAL4Aph-4-c232 does not affect fate specification, cell proliferation, dendrite formation, or axon projection of R neurons.

      pdm3Scer\UAS.T:Avic\GFP-CFP overexpression in Scer\GAL4lilli-189Y and Scer\GAL4Aph-4-c232-expressing neurons has no effect on presynaptic patterning in the ellipsoid body.

      pdm31; Scer\GAL4pdm3, pdm3Scer\UAS.T:Avic\GFP-CFP/Scer\GAL80ts.αTub84B flies raised at 18[o]C (where Scer\GAL80ts.αTub84B is active) throughout development fail to rescue ellipsoid body structure. In contrast, when the flies are cultured at 29[o]C throughout development, the ellipsoid body structure is fully rescued. Rescue also occurs when the flies are only shifted to 29[o]C for the first 48 hours after pupal formation. The ellipsoid body structure is not rescued when the flies are shifted to 29[o]C after 96 hours at 18[o]C.

      (Chen et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      pdm3UAS.CFP/Scer\GAL4pdm3 rescues pdm31

      (Chen et al., 2012)
      Fails to rescue

      pdm3UAS.CFP/Scer\GAL4c105 fails to rescue pdm31

      (Chen et al., 2012)

      pdm3UAS.CFP/Scer\GAL4lilli-189Y fails to rescue pdm31

      (Chen et al., 2012)

      pdm3UAS.CFP/Scer\GAL4Alp4-c232 fails to rescue pdm31

      (Chen et al., 2012)
      Comments

      Expression of pdm3Scer\UAS.T:Avic\GFP-CFP in pdm31, driven by Scer\GAL4pdm3, rescues the ellipsoid body structure to its full doughnut-like structure.

      pdm31; Scer\GAL4pdm3, pdm3Scer\UAS.T:Avic\GFP-CFP/Scer\GAL80ts.αTub84B flies raised at 18[o]C (where Scer\GAL80ts.αTub84B is active) throughout development fail to rescue ellipsoid body structure. In contrast, when the flies are cultured at 29[o]C throughout development, the ellipsoid body structure is fully rescued. Rescue also occurs when the flies are only shifted to 29[o]C for the first 48 hours after pupal formation. The ellipsoid body structure is not rescued when the flies are shifted to 29[o]C after 96 hours at 18[o]C.

      (Chen et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pdm3Scer\UAS.T:Avic\GFP-CFP
      pdm3UAS.CFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)