FlyBase Allele Report: Dmel\comm[UAS.cUa]

General Information

Symbol

Dmel\comm^UAS.cUa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Unknown

FlyBase ID

FBal0280828

Feature type

allele

Associated gene

Dmel\comm

Associated Insertion(s)

Carried in Construct

P{UAS-comm.U}

Also Known As

UAS-Comm

Key Links

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-comm.U}

Cytology

Description

UAS regulatory sequences drive expression of comm.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

comm

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | embryonic stage, with Scer\GAL4^15J2

(Hiramoto and Hiromi, 2006)

Phenotype Manifest In

dMP2 neuron, with Scer\GAL4^15J2

(Hiramoto and Hiromi, 2006)

Detailed Description

Statement

Reference

Expression of comm^Scer\UAS.cUa under the control of Scer\GAL4^15J2 causes contralateral misprojection of the dMP2 neuron along the anterior commissure of the next segment in 93.8% of cases. The pCC axon correctly follows the longitudinal pathway and contacts the dMP2 axon.

(Hiramoto and Hiromi, 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔIg2-5.Tag:HA} has abnormal neuroanatomy | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔFn1-3.Tag:HA} has abnormal neuroanatomy | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔIg2ΔFn3.Tag:HA} has abnormal neuroanatomy | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^Tag:HA has abnormal neuroanatomy | embryonic stage phenotype

(Brown and Evans, 2020, Brown et al., 2015)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^ΔIg1.Tag:HA has abnormal neuroanatomy | embryonic stage phenotype

(Brown et al., 2015)

Phenotype Manifest In

Other

Statement

Reference

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔIg2-5.Tag:HA} has axon | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔIg2-5.Tag:HA} has embryonic/larval midline of ventral nerve cord | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^Tag:HA has axon | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^Tag:HA has embryonic/larval midline of ventral nerve cord | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔFn1-3.Tag:HA} has axon | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔFn1-3.Tag:HA} has embryonic/larval midline of ventral nerve cord | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔIg2ΔFn3.Tag:HA} has axon | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^{ΔIg2ΔFn3.Tag:HA} has embryonic/larval midline of ventral nerve cord | embryonic stage phenotype

(Brown and Evans, 2020)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^Tag:HA has larval ventral nerve cord | embryonic stage phenotype

(Brown et al., 2015)

Scer\GAL4^elav.PLu, comm^UAS.cUa, robo1^ΔIg1.Tag:HA has larval ventral nerve cord | embryonic stage phenotype

(Brown et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of comm^Scer\UAS.cUa (under the control of Scer\GAL4^elav.PLu) and robo1^T:Ivir\HA1 or robo1^{ΔIg1.T:Ivir\HA1} in embryos results in an increase in axon midline crossing and corresponding thickening of commissures in the ventral nerve cord.

(Brown et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

comm^Scer\UAS.cUa

comm^UAS.cUa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

References (5)

Report Sections

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