FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\cnoUAS.GFP
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General Information
Symbol
Dmel\cnoUAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0294979
Feature type
allele
Associated gene
Dmel\cno
Associated Insertion(s)
Carried in Construct
P{UAS-GFP-cno.WT}
Key Links
Transgenic product class
cDNA
(Keder et al., 2015)
wild_type
(Keder et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Keder et al., 2015)
wild_type
(Keder et al., 2015)
Mutagen
in vitro construct
(Keder et al., 2015, Pérez-Gómez et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-GFP-cno.WT}
Cytology
Description

UAS regulatory sequences drive expression of a full-length, wild-type cno cDNA, which is tagged with GFP.

(Keder et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
cno
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of cnoUAS.GFP under the control of Scer\GAL4αTub84B.PL in somatic clones of pupal retina leads to excessive numbers of lattice cells at some edges and loss of cells at others different than controls.

      (Letizia et al., 2019)

      Expression of cnoScer\UAS.T:Avic\GFP, under the neuroepithelia-specific driver Scer\GAL4C855a results in changes in the proneural wave progression in the optic lobe. The proneural wave appears delayed compared to control flies, with the concomitant decrease in the differentiation of medulla neuroblasts.

      Expression of cnoScer\UAS.T:Avic\GFP in the glia (under the control of Scer\GAL4repo.PU) leads to a significant decrease in the number of repo-positive and phospho-His3-positive cells (indicative of mitosis), compared to control optic lobes.

      (Pérez-Gómez et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cnoScer\UAS.T:Avic\GFP
      cnoUAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (4)