FlyBase Allele Report: Scer\GAL4[C855a]

Drives expression in neuroepithelial cells in the larval optic anlage, in the peripodial epithelium of imaginal discs, and in oocyte associated follicle cells.

(FlyBase Curators, 2017)

ScerGAL4^C855a drives expression from the end of the first instar onwards in the neuroepithelial cells of the outer optic anlage (OPC), and in lamina precursor cells.

(Wang et al., 2011)

During oogenesis, ScerGAL4^C855a drives expression in posterior terminal cells at oogenesis stage 9-10, and in oocyte associated follicle cells (columnar cells) at stage 10. In the male reproductive tract, ScerGAL4^C855a drives expression in the seminal vesicle and the testis sheath muscle. At larval stages, ScerGAL4^C855a drives expression in the optic lobes, the brain, in a wide region of the wing disc centered on the A/P boundary, and in the peripodial epithelium of the eye and leg discs.

(Hrdlicka et al., 2002)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell adhesion | late third instar larval stage, with Optix^FL.UAS

(Gold and Brand, 2014)

abnormal cell polarity | late third instar larval stage, with Optix^FL.UAS

(Gold and Brand, 2014)

abnormal cell shape | late third instar larval stage, with Optix^FL.UAS

(Gold and Brand, 2014)

abnormal developmental rate, with cno^GD1395

(Pérez-Gómez et al., 2013)

abnormal developmental rate, with cno^UAS.GFP

(Pérez-Gómez et al., 2013)

abnormal developmental rate | prepupal stage, with shd^UAS.cOa

(Akagi et al., 2016)

abnormal locomotor behavior | adult stage, with rk^GD14383

(Loveall and Deitcher, 2010)

abnormal neuroanatomy | larval stage, with mir-ban^D.UAS.EGFP

(Richter et al., 2011)

abnormal neuroanatomy | larval stage, with mnb^NIG.7826R

(Brown et al., 2024)

abnormal neuroanatomy | larval stage, with N^NIG.3936R

(Wang et al., 2011)

abnormal neuroanatomy | larval stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

abnormal neuroanatomy | larval stage, with yki^{S168A.UAS.RFP(Unk)}

(Richter et al., 2011)

abnormal neuroanatomy | late third instar larval stage, with Optix^FL.UAS

(Gold and Brand, 2014)

abnormal neuroanatomy | pharate adult stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

abnormal neuroanatomy | somatic clone | third instar larval stage, with Ras85D^V12.UAS

(Morante et al., 2013)

abnormal neuroanatomy | third instar larval stage, with Egfr::tor^act.UAS

(Morante et al., 2013)

abnormal neuroanatomy | third instar larval stage, with Egfr^DN.UAS

(Morante et al., 2013)

abnormal neuroanatomy | third instar larval stage, with N^KK102890

(Morante et al., 2013)

abnormal neuroanatomy | third instar larval stage, with Ras85D^V12.UAS

(Morante et al., 2013)

abnormal neuroanatomy | third instar larval stage, with Treh^GD5118

(Chen et al., 2014)

abnormal size | larval stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

abnormal size | pharate adult stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

decreased cell number | larval stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

decreased cell number | third instar larval stage, with Delta^UAS.cUa

(Wang et al., 2011)

decreased size | larval stage, with mnb^NIG.7826R

(Brown et al., 2024)

increased cell number | larval stage, with Gyc89Db^UAS.cVa

(Prieto et al., 2024)

increased occurrence of cell division | larval stage, with Gyc89Db^UAS.cVa

(Prieto et al., 2024)

increased size | larval stage, with Gyc89Db^UAS.cVa

(Prieto et al., 2024)

lethal, with N^ΔE.UAS

(Wang et al., 2011)

male fertile, with kirre^GD2595

(Susic-Jung et al., 2012)

male fertile, with sns^KK108577

(Susic-Jung et al., 2012)

partially lethal - majority die, with tll^RNAi.UAS

(Guillermin et al., 2015)

semi-sterile, with Nox^RNAi.UAS.cRa

(Ritsick et al., 2007)

visible, with rk^GD14383

(Loveall and Deitcher, 2010)

Phenotype Manifest In

adult optic lobe, with cno^GD1395

(Pérez-Gómez et al., 2013)

adult optic lobe, with cno^UAS.GFP

(Pérez-Gómez et al., 2013)

adult optic lobe, with Ser^sec.UAS

(Pérez-Gómez et al., 2013)

adult optic lobe | pharate adult stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

embryonic/larval optic lobe | larval stage, with Gyc89Db^UAS.cVa

(Prieto et al., 2024)

embryonic/larval optic lobe | larval stage, with mir-ban^D.UAS.EGFP

(Richter et al., 2011)

embryonic/larval optic lobe | temperature conditional, with N^ΔE.UAS, Scer\GAL80^ts.αTub84B

(Wang et al., 2011)

lamina | pharate adult stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

lamina | third instar larval stage, with Treh^GD5118

(Chen et al., 2014)

lamina anlage, with N^NIG.3936R

(Wang et al., 2011)

lamina anlage, with RPA3^GD4799

(Zhou and Luo, 2013)

lamina forming neuroblast | larval stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

lamina forming neuroblast | larval stage | somatic clone, with tll^RNAi.UAS

(Guillermin et al., 2015)

lamina furrow | larval stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

larval brain, with Gyc89Db^UAS.cVa

(Prieto et al., 2024)

larval brain, with mnb^NIG.7826R

(Brown et al., 2024)

larval brain | somatic clone | third instar larval stage, with Ras85D^V12.UAS

(Morante et al., 2013)

larval brain | third instar larval stage, with Egfr::tor^act.UAS

(Morante et al., 2013)

larval brain | third instar larval stage, with Egfr^DN.UAS

(Morante et al., 2013)

larval brain | third instar larval stage, with N^KK102890

(Morante et al., 2013)

larval brain | third instar larval stage, with Ras85D^V12.UAS

(Morante et al., 2013)

larval central brain, with Gyc89Db^UAS.cVa

(Prieto et al., 2024)

larval inner optic anlage, with btl::Egfr^λ.UAS

(Richter et al., 2011)

larval inner optic anlage, with tll^RNAi.UAS

(Guillermin et al., 2015)

larval inner optic anlage, with yki^{S168A.UAS.RFP(Unk)}

(Richter et al., 2011)

larval neuroblast | ectopic | somatic clone | third instar larval stage, with Ras85D^V12.UAS

(Morante et al., 2013)

larval neuroblast | ectopic | third instar larval stage, with Egfr::tor^act.UAS

(Morante et al., 2013)

larval neuroblast | ectopic | third instar larval stage, with Ras85D^V12.UAS

(Morante et al., 2013)

larval neuroblast | increased number, with Gyc89Db^UAS.cVa

(Prieto et al., 2024)

larval neuroblast | third instar larval stage, with Egfr^DN.UAS

(Morante et al., 2013)

larval optic anlage, with tll^RNAi.UAS

(Guillermin et al., 2015)

larval outer optic anlage, with Delta^UAS.cUa

(Wang et al., 2011)

larval outer optic anlage, with hop^Tum.UAS

(Richter et al., 2011)

larval outer optic anlage, with N^NIG.3936R

(Wang et al., 2011)

larval outer optic anlage, with tll^RNAi.UAS

(Guillermin et al., 2015)

larval outer optic anlage, with yki^{S168A.UAS.RFP(Unk)}

(Richter et al., 2011)

larval outer optic anlage | late third instar larval stage, with Optix^FL.UAS

(Gold and Brand, 2014)

larval outer optic anlage | third instar larval stage, with Treh^GD5118

(Chen et al., 2014)

medulla | pharate adult stage, with tll^RNAi.UAS

(Guillermin et al., 2015)

medulla | third instar larval stage, with Treh^GD5118

(Chen et al., 2014)

medulla anlage, with Delta^UAS.cUa

(Wang et al., 2011)

medulla anlage, with N^NIG.3936R

(Wang et al., 2011)

medulla anlage | temperature conditional, with N^ΔE.UAS, Scer\GAL80^ts.αTub84B

(Wang et al., 2011)

metathoracic tarsal segment, with rk^GD14383

(Loveall and Deitcher, 2010)

optic lobe neuroepithelial cell | larval stage, with mnb^NIG.7826R

(Brown et al., 2024)

optic lobe neuroepithelial cell | late third instar larval stage, with Optix^FL.UAS

(Gold and Brand, 2014)

proneural cluster, with cno^GD1395

(Pérez-Gómez et al., 2013)

proneural cluster, with cno^UAS.GFP

(Pérez-Gómez et al., 2013)

proneural cluster, with Ser^sec.UAS

(Pérez-Gómez et al., 2013)

wing, with rk^GD14383

(Loveall and Deitcher, 2010)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^C855a, mnb^NIG.7826R has decreased size | larval stage phenotype, enhanceable by Rala^S25N.UAS, Scer\GAL4^C855a

(Brown et al., 2024)

NOT Enhanced by

Statement

Reference

Scer\GAL4^C855a, mnb^NIG.7826R has decreased size | larval stage phenotype, non-enhanceable by Reps^KK101677, Scer\GAL4^C855a

(Brown et al., 2024)

Scer\GAL4^C855a, mnb^NIG.7826R has decreased size | larval stage phenotype, non-enhanceable by Rlip^KK101635, Scer\GAL4^C855a

(Brown et al., 2024)

Enhancer of

Statement

Reference

Rala^S25N.UAS, Scer\GAL4^C855a is an enhancer of decreased size | larval stage phenotype of Scer\GAL4^C855a, mnb^NIG.7826R

(Brown et al., 2024)

NOT Enhancer of

Statement

Reference

Reps^KK101677, Scer\GAL4^C855a is a non-enhancer of decreased size | larval stage phenotype of Scer\GAL4^C855a, mnb^NIG.7826R

(Brown et al., 2024)

Rlip^KK101635, Scer\GAL4^C855a is a non-enhancer of decreased size | larval stage phenotype of Scer\GAL4^C855a, mnb^NIG.7826R

(Brown et al., 2024)

Suppressor of

Statement

Reference

Scer\GAL4^C855a/BacA\p35^UAS.cHa is a suppressor of increased cell death | third instar larval stage phenotype of asp^E3

(Rujano et al., 2013)

Scer\GAL4^C855a/BacA\p35^UAS.cHa is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of asp^E3

(Rujano et al., 2013)

Scer\GAL4^C855a/ex^UAS.cBa is a suppressor of abnormal neuroanatomy phenotype of l(3)mbt^GM76

(Richter et al., 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^C855a, mnb^NIG.7826R has larval brain phenotype, enhanceable by Rala^S25N.UAS, Scer\GAL4^C855a

(Brown et al., 2024)

NOT Enhanced by

Statement

Reference

Scer\GAL4^C855a, mnb^NIG.7826R has larval brain phenotype, non-enhanceable by Rlip^KK101635, Scer\GAL4^C855a

(Brown et al., 2024)

Scer\GAL4^C855a, mnb^NIG.7826R has larval brain phenotype, non-enhanceable by Reps^KK101677, Scer\GAL4^C855a

(Brown et al., 2024)

Enhancer of

Statement

Reference

Rala^S25N.UAS, Scer\GAL4^C855a is an enhancer of larval brain phenotype of Scer\GAL4^C855a, mnb^NIG.7826R

(Brown et al., 2024)

NOT Enhancer of

Statement

Reference

Rlip^KK101635, Scer\GAL4^C855a is a non-enhancer of larval brain phenotype of Scer\GAL4^C855a, mnb^NIG.7826R

(Brown et al., 2024)

Reps^KK101677, Scer\GAL4^C855a is a non-enhancer of larval brain phenotype of Scer\GAL4^C855a, mnb^NIG.7826R

(Brown et al., 2024)

Suppressor of

Statement

Reference

Scer\GAL4^C855a/BacA\p35^UAS.cHa is a suppressor of larval brain | third instar larval stage phenotype of asp^E3

(Rujano et al., 2013)

Scer\GAL4^C855a/ex^UAS.cBa is a suppressor of embryonic/larval optic lobe phenotype of l(3)mbt^GM76

(Richter et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to rescue

Scer\GAL4^C855a/Pngl^UASp.cFa fails to rescue Pngl^unspecified

(Funakoshi et al., 2010)

Scer\GAL4^C855a/Pngl^{UASp.Tag:FLAG} fails to rescue Pngl^unspecified

(Funakoshi et al., 2010)

Scer\GAL4^C855a/Pngl^C303A.UASp fails to rescue Pngl^unspecified

(Funakoshi et al., 2010)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

6990

w¹¹¹⁸; P{GawB}C855a

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

GAL4^C855a

(Richter et al., 2011)

GAL4^c855a

(Prieto et al., 2024, Gonzalez et al., 2023)

Scer\GAL4^C855a

Name Synonyms

Secondary FlyBase IDs

References (40)

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