FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\brp+t83.4
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General Information
Symbol
Dmel\brp+t83.4
Species
D. melanogaster
Name
FlyBase ID
FBal0296089
Feature type
allele
Associated gene
Dmel\brp
Associated Insertion(s)
Carried in Construct
PBac{brp.rescue}
Also Known As
brprescue, brp P[acman]
Key Links
Transgenic product class
genomic_DNA
(Matkovic et al., 2013)
wild_type
(Matkovic et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Matkovic et al., 2013)
wild_type
(Matkovic et al., 2013)
Mutagen
in vitro construct
(Matkovic et al., 2013)
Progenitor genotype
Carried in construct
PBac{brp.rescue}
Cytology
Description

83.4kb genomic fragment which includes the entire brp gene plus the flanking Wnt2 and CG1888 genes.

(Matkovic et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
brp
Encoded product / tool
brp
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Alzheimer's disease 1
      modeled by Hsap\APPAβ42.E693G.UAS.VTR
      (Huang et al., 2022)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      brp+t83.4 is a suppressor of short lived | male phenotype of incf00285

      (Huang et al., 2022)

      brp+t83.4 is a suppressor of short lived | male phenotype of wakeEY02219

      (Huang et al., 2022)
      NOT Suppressor of
      Statement
      Reference

      brp+t83.4 is a non-suppressor of short lived phenotype of Hsap\APPAβ42.E693G.UAS.VTR, Scer\GAL4elav-C155

      (Huang et al., 2022)

      brp+t83.4 is a non-suppressor of short lived phenotype of Atg7d06996

      (Huang et al., 2022)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      brp+t83.4 rescues brpc04298

      (Huang et al., 2022)
      Comments

      brp+t83.4 rescues brp null alleles to adult vitality and fertility.

      (Matkovic et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      brp+t83.4
      brpp[acman]WT
      (Driller et al., 2019)
      brprescue
      (Driller et al., 2019, Matkovic et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)