FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4ort.C1a
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General Information
Symbol
Scer\GAL4ort.C1a
Species
S. cerevisiae
Name
FlyBase ID
FBal0296543
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{ort-GAL4.C1a}
Also Known As
ortC1a-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Karuppudurai et al., 2014)
Progenitor genotype
Carried in construct
P{ort-GAL4.C1a}
Cytology
Description

The ort C1 enhancer followed by the hs43 minimal promoter regulate expression of a GAL4 driver.

(Karuppudurai et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
ort
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      transmedullary neuron Tm5a
      (Karuppudurai et al., 2014, Ting et al., 2014)
      transmedullary neuron Tm5b
      (Karuppudurai et al., 2014, Ting et al., 2014)
      transmedullary neuron Tm5c
      (Karuppudurai et al., 2014, Ting et al., 2014)
      transmedullary neuron Tm20
      (Karuppudurai et al., 2014, Ting et al., 2014)
      lobula layer 4
      (Karuppudurai et al., 2014)
      lobula layer 5
      (Karuppudurai et al., 2014)
      medulla layer M1
      (Karuppudurai et al., 2014)
      medulla layer M3
      (Karuppudurai et al., 2014)
      medulla layer M6
      (Karuppudurai et al., 2014)
      medulla layer M8
      (Karuppudurai et al., 2014)
      Additional Information
      Statement
      Reference

      Clonal analysis using ScerGAL4ort.C1a shows expression in transmedullary neurons Tm5a and Tm5b. These extend dendrites along photoreceptor axons arborizing in medulla layers M3, M6 and M8 while their axons branch out in lobula layer 5. Expression in transmedullary neuron Tm5c shows dendrites extending to medulla layers M1, M3 and M6, the axon bifurcates in lobula layer 4 and terminates in lobula layers 5 and 6.

      (Karuppudurai et al., 2014)

      ScerGAL4ort.C1a drives expression in toy positive transmedullary neuron Tm20.

      (Ting et al., 2014)
       
      Marker for
      transmedullary neuron Tm20
      (Karuppudurai et al., 2014)
      transmedullary neuron Tm5a
      (Karuppudurai et al., 2014)
      transmedullary neuron Tm5b
      (Karuppudurai et al., 2014)
      transmedullary neuron Tm5c
      (Karuppudurai et al., 2014)
      Reflects expression of
      ort
      (Karuppudurai et al., 2014, Ting et al., 2014)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Ctet\tetXTNT-LC.UAS) of Scer\GAL4ort.C1a cells in adults results in a significant reduction in short-term aversive visual (blue/green) memory, compared to controls, with no effect on the optomotor response to blue-green patterns.

      (Melnattur et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4ort.C1a
      Name Synonyms
      Secondary FlyBase IDs
        References (7)