FlyBase Allele Report: Dmel\Ptp61F[4-10]

Imprecise excision of P{EP}Ptp61F^GE29807. The 5' end of the progenitor P{EP} element and Ptp61F and intact, but the coding region of Ptp61F is completely removed.

(Tchankouo-Nguetcheu et al., 2014)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

3L:1,334,923..1,349,604 [-]

Comment:

Deletion resulting from the imprecise excision of P{EP}Ptp61F^GE29807, which removes the entire coding region of Ptp61F as well as CG2199 and l(3)02640.

(Tchankouo-Nguetcheu et al., 2014)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Tchankouo-Nguetcheu et al., 2014)

lethal (with Df(3L)BSC178)

(Tchankouo-Nguetcheu et al., 2014)

lethal (with Df(3L)BSC289)

(Tchankouo-Nguetcheu et al., 2014)

lethal (with Df(3L)ED207)

(Tchankouo-Nguetcheu et al., 2014)

lethal (with Df(3L)ED4196)

(Tchankouo-Nguetcheu et al., 2014)

viable (with Ptp61F^GE29807)

(Tchankouo-Nguetcheu et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Ptp61F[+]/Ptp61F^4-10 is an enhancer of abnormal size phenotype of InR^A1325D.GMR

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of abnormal size phenotype of Akt^GMR.Exel

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of abnormal size phenotype of Pi3K92E^CAAX.GMR

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of abnormal size phenotype of Abl^UAS.cFa

(Tchankouo-Nguetcheu et al., 2014)

Suppressor of

Statement

Reference

Ptp61F[+]/Ptp61F^4-10 is a suppressor of abnormal size | dominant phenotype of Egfr^E1

(Tchankouo-Nguetcheu et al., 2014)

Other

Statement

Reference

Ptp61F[+]/Ptp61F^4-10, rl^Sem has abnormal size phenotype

(Tchankouo-Nguetcheu et al., 2014)

Phenotype Manifest In

Enhancer of

Statement

Reference

Ptp61F[+]/Ptp61F^4-10 is an enhancer of eye phenotype of InR^A1325D.GMR

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of wing vein phenotype of rl^Sem

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of wing vein | ectopic phenotype of rl^Sem

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of eye phenotype of Akt^GMR.Exel

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of eye phenotype of Pi3K92E^CAAX.GMR

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of eye phenotype of Abl^UAS.cFa

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is an enhancer of eye phenotype of Ras85D^V12.sev

(Tchankouo-Nguetcheu et al., 2014)

NOT Enhancer of

Statement

Reference

Ptp61F[+]/Ptp61F^4-10 is a non-enhancer of eye phenotype of pnt¹²⁷⁷/pnt^Δ88

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is a non-enhancer of eye phenotype of InR^K1409A.GMR

(Tchankouo-Nguetcheu et al., 2014)

Suppressor of

Statement

Reference

Ptp61F[+]/Ptp61F^4-10 is a suppressor of eye phenotype of Egfr^E1

(Tchankouo-Nguetcheu et al., 2014)

NOT Suppressor of

Statement

Reference

Ptp61F[+]/Ptp61F^4-10 is a non-suppressor of eye phenotype of InR^K1409A.GMR

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F[+]/Ptp61F^4-10 is a non-suppressor of eye phenotype of pnt¹²⁷⁷/pnt^Δ88

(Tchankouo-Nguetcheu et al., 2014)

Other

Statement

Reference

Ptp61F[+]/Ptp61F^4-10, rl^Sem has eye phenotype

(Tchankouo-Nguetcheu et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

rl^Sem in combination with Ptp61F^4-10/+ results in larger than normal eyes.

(Tchankouo-Nguetcheu et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

56511

w^*; Df(3L)Ptp61F^4-10, P{5'EP}Ptp61F^4-10/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

PTP61F^4-10

(Tchankouo-Nguetcheu et al., 2014)

Ptp61F^4-10

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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