FlyBase Allele Report: Dmel\Akt[UAS.cUa]

General Information

Symbol

Dmel\Akt^UAS.cUa

Species

D. melanogaster

Name

UAS construct a of Unknown

FlyBase ID

FBal0299619

Feature type

allele

Associated gene

Dmel\Akt

Associated Insertion(s)

Carried in Construct

P{UAS-Akt.U}

Also Known As

UAS-Akt, UAS-Akt1

Key Links

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-Akt.U}

Cytology

Description

UAS sequences regulate expression of Akt.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Akt

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell size | adult stage, with Scer\GAL4^GMR.PU

(Aron et al., 2010)

visible, with Scer\GAL4^GMR.PU

(Aron et al., 2010)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PU

(Aron et al., 2010)

ommatidium, with Scer\GAL4^GMR.PU

(Aron et al., 2010)

Detailed Description

Statement

Reference

Expression of Akt1^Scer\UAS.cUa driven by Scer\GAL4^GMR.PU leads to a significant increase in eye and ommatidial size compared to controls.

(Aron et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Akt^UAS.cUa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by DJ-1α^UAS.cMa, Scer\GAL4^GMR.PU

(Aron et al., 2010)

Akt^UAS.cUa, Scer\GAL4^GMR.PU has increased cell size | adult stage phenotype, non-enhanceable by DJ-1α^UAS.cMa, Scer\GAL4^GMR.PU

(Aron et al., 2010)

Akt^UAS.cUa, Scer\GAL4^GMR.PU has visible phenotype, non-enhanceable by dj-1β^UAS.cMa, Scer\GAL4^GMR.PU

(Aron et al., 2010)

Akt^UAS.cUa, Scer\GAL4^GMR.PU has increased cell size | adult stage phenotype, non-enhanceable by dj-1β^UAS.cMa, Scer\GAL4^GMR.PU

(Aron et al., 2010)

NOT suppressed by

Statement

Reference

Akt^UAS.cUa, Scer\GAL4^GMR.PU has visible phenotype, non-suppressible by dj-1β^Δ93/dj-1β^Δ93

(Aron et al., 2010)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Akt^UAS.cUa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by DJ-1α^UAS.cMa, Scer\GAL4^GMR.PU

(Aron et al., 2010)

Akt^UAS.cUa, Scer\GAL4^GMR.PU has ommatidium phenotype, non-enhanceable by DJ-1α^UAS.cMa, Scer\GAL4^GMR.PU

(Aron et al., 2010)

Akt^UAS.cUa, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by dj-1β^UAS.cMa, Scer\GAL4^GMR.PU

(Aron et al., 2010)

Akt^UAS.cUa, Scer\GAL4^GMR.PU has ommatidium phenotype, non-enhanceable by dj-1β^UAS.cMa, Scer\GAL4^GMR.PU

(Aron et al., 2010)

NOT suppressed by

Statement

Reference

Akt^UAS.cUa, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by dj-1β^Δ93/dj-1β^Δ93

(Aron et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of dj-1β^Scer\UAS.cMa or DJ-1α^Scer\UAS.cMa or presence of dj-1β^Δ93/dj-1β^Δ93 does not enhance eye and ommatidial size phenotypes in flies with expression of Akt1^Scer\UAS.cUa driven by Scer\GAL4^GMR.PU.

(Aron et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Akt1^Scer\UAS.cUa

Akt1^UAS.cUa

Akt^UAS.cUa

Name Synonyms

UAS construct a of Unknown

Secondary FlyBase IDs

References (11)

Report Sections

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