FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Atg7UAS.cCa
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General Information
Symbol
Dmel\Atg7UAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Chen
FlyBase ID
FBal0299701
Feature type
allele
Associated gene
Dmel\Atg7
Associated Insertion(s)
Carried in Construct
P{UAS-Atg7.C}
Key Links
Transgenic product class
cDNA
(Chen et al., 2012)
wild_type
(Chen et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Chen et al., 2012)
wild_type
(Chen et al., 2012)
Mutagen
in vitro construct
(Chen et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Atg7.C}
Cytology
Description

UAS regulatory sequences drive expression of the full-length Atg7 coding sequence (derived from cDNA clone RE27292).

(Chen et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Atg7
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  neurodegenerative disease
      modeled by Zzzz\CAG41Q.UAS.Tag:HA
      (Chen et al., 2012)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Atg7Scer\UAS.cCa under the control of either Scer\GAL4hs.PU or Scer\GAL4Appl.PU results in long lived adults, as compared to controls

      (Chen et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Atg7UAS.cCa, Scer\GAL4GMR.PU is a non-suppressor of visible phenotype of Scer\GAL4GMR.PU, Zzzz\CAG63Q.UAS.Tag:HA

      (Chen et al., 2012)
      Other
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Atg7UAS.cCa, Scer\GAL4GMR.PU is a non-suppressor of eye phenotype of Scer\GAL4GMR.PU, Zzzz\CAG63Q.UAS.Tag:HA

      (Chen et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Flies expressing both Atg7Scer\UAS.cCa and Hsp27Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PU have a normal eye phenotype.

      Co-expression of Atg7Scer\UAS.cCa fully rescues the rough eye phenotype caused by expression of Hsp27GD11327 under the control of Scer\GAL4GMR.PU.

      (Chen et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference

      The mild mosaic eye pigmentation defect caused by expression of Zzzz\CAG41Q.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PU is rescued by co-expression of Atg7Scer\UAS.cCa.

      The rough eye defect caused by expression of Zzzz\CAG63Q.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PU is not rescued by co-expression of Atg7Scer\UAS.cCa.

      (Chen et al., 2012)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Atg7Scer\UAS.cCa
      Atg7UAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Chen
      Secondary FlyBase IDs
        References (1)