FlyBase Allele Report: Scer\GAL4[Appl.PU]

General Information

Symbol

Scer\GAL4^Appl.PU

Species

S. cerevisiae

Name

β amyloid protein precursor-like promoter construct of Unknown

FlyBase ID

FBal0298301

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Appl-GAL4.U}

Also Known As

Appl-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{Appl-GAL4.U}

Cytology

Description

Appl regulatory sequences control expression of a GAL4 driver.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

Appl

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal oxidative stress response | adult stage, with Gp93^GS16347

(Xu et al., 2025)

chemical resistant, with Ku80^JF02790

(Juraeva et al., 2015)

increased cell death | third instar larval stage, with Appl^sd.UAS

(Wang et al., 2015)

increased rate of adult locomotory behavior, with Gp93^GS16347

(Xu et al., 2025)

long lived, with Atg7^UAS.cCa

(Chen et al., 2012)

long lived, with Gp93^GS16347

(Xu et al., 2025)

short lived, with Hsap\HTT^{171aa.138Q.UAS.Tag:HA}

(Heidari et al., 2015)

short lived, with Hsap\HTT^Q93.ex1.UAS

(Heidari et al., 2015)

short lived, with Hsap\TARDBP^UAS.cHa

(Deshpande et al., 2016)

short lived, with Hsap\TARDBP^UAS.cLa

(Deshpande et al., 2016)

viable, with Pka-C3^NIG.6117R

(Cassar et al., 2018)

Phenotype Manifest In

larval ventral nerve cord | third instar larval stage, with Appl^sd.UAS

(Wang et al., 2015)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^Appl.PU/Hsap\PNPLA6^F1M.UAS is an enhancer of abnormal neuroanatomy | adult stage phenotype of sws¹

(Topaloglu et al., 2014)

NOT Enhancer of

Statement

Reference

Hsap\PNPLA6^F2M1.UAS/Scer\GAL4^Appl.PU is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of sws¹

(Topaloglu et al., 2014)

Hsap\PNPLA6^F2M2.UAS/Scer\GAL4^Appl.PU is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of sws¹

(Topaloglu et al., 2014)

Suppressor of

Statement

Reference

Hsap\PNPLA6^UAS.cTa/Scer\GAL4^Appl.PU is a suppressor | partially of abnormal neuroanatomy | adult stage phenotype of sws¹

(Topaloglu et al., 2014)

NOT Suppressor of

Statement

Reference

Hsap\PNPLA6^F2M1.UAS/Scer\GAL4^Appl.PU is a non-suppressor of abnormal neuroanatomy | adult stage phenotype of sws¹

(Topaloglu et al., 2014)

Hsap\PNPLA6^F2M2.UAS/Scer\GAL4^Appl.PU is a non-suppressor of abnormal neuroanatomy | adult stage phenotype of sws¹

(Topaloglu et al., 2014)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^Appl.PU/Hsap\PNPLA6^F1M.UAS is an enhancer of adult brain phenotype of sws¹

(Topaloglu et al., 2014)

NOT Enhancer of

Statement

Reference

Hsap\PNPLA6^F2M1.UAS/Scer\GAL4^Appl.PU is a non-enhancer of adult brain phenotype of sws¹

(Topaloglu et al., 2014)

Hsap\PNPLA6^F2M2.UAS/Scer\GAL4^Appl.PU is a non-enhancer of adult brain phenotype of sws¹

(Topaloglu et al., 2014)

Suppressor of

Statement

Reference

Hsap\PNPLA6^UAS.cTa/Scer\GAL4^Appl.PU is a suppressor | partially of adult brain phenotype of sws¹

(Topaloglu et al., 2014)

NOT Suppressor of

Statement

Reference

Hsap\PNPLA6^F2M1.UAS/Scer\GAL4^Appl.PU is a non-suppressor of adult brain phenotype of sws¹

(Topaloglu et al., 2014)

Hsap\PNPLA6^F2M2.UAS/Scer\GAL4^Appl.PU is a non-suppressor of adult brain phenotype of sws¹

(Topaloglu et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^Appl.PU

Name Synonyms

β amyloid protein precursor-like promoter construct of Unknown

Secondary FlyBase IDs

References (21)

Report Sections

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