FlyBase Allele Report: Dmel\Uev1A[UAS.cMa]

General Information

Symbol

Dmel\Uev1A^UAS.cMa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Ma

FlyBase ID

FBal0299703

Feature type

allele

Associated gene

Dmel\Uev1A

Associated Insertion(s)

Carried in Construct

P{UAS-Uev1a.M}

Key Links

Allele class

Mutagen

in vitro construct - regulatory fusion

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Ma et al., 2012)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{UAS-Uev1a.M}

Cytology

Nature of the lesion

Statement

Reference

UAS regulatory sequences drive expression of Uev1A.

(Ma et al., 2012)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Uev1A

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^ptc-559.1, Uev1A^UAS.cMa, ben^UAS.cUa has visible phenotype, suppressible by Scer\GAL4^ptc-559.1/Traf6^dsRNA.UAS

(Ma et al., 2013)

Scer\GAL4^ptc-559.1, Uev1A^UAS.cMa, ben^UAS.cUa has visible phenotype, suppressible by Scer\GAL4^ptc-559.1/Tak1^NIG.1388R

(Ma et al., 2013)

Enhancer of

Statement

Reference

ben^UAS.cUa, Uev1A^UAS.cMa, Scer\GAL4^GMR.PF is an enhancer of increased cell death phenotype of Scer\GAL4^GMR.PF, nopo^UAS.cUa

(Ma et al., 2012)

NOT Enhancer of

Statement

Reference

Uev1A^UAS.cMa/Scer\GAL4^GMR.PF is a non-enhancer of increased cell death phenotype of Scer\GAL4^GMR.PF, nopo^UAS.cUa

(Ma et al., 2012)

Other

Statement

Reference

Scer\GAL4^ptc-559.1, Uev1A^UAS.cMa, ben^UAS.cUa has visible phenotype

(Ma et al., 2013)

Scer\GAL4^ptc-559.1, Traf6^dsRNA.UAS, Uev1A^UAS.cMa, ben^UAS.cUa has visible phenotype

(Ma et al., 2013)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^ptc-559.1, Uev1A^UAS.cMa, ben^UAS.cUa has anterior crossvein phenotype, suppressible by Scer\GAL4^ptc-559.1/Traf6^dsRNA.UAS

(Ma et al., 2013)

Scer\GAL4^ptc-559.1, Uev1A^UAS.cMa, ben^UAS.cUa has anterior crossvein phenotype, suppressible by Scer\GAL4^ptc-559.1/Tak1^NIG.1388R

(Ma et al., 2013)

Enhancer of

Statement

Reference

ben^UAS.cUa, Uev1A^UAS.cMa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, nopo^UAS.cUa

(Ma et al., 2012)

NOT Enhancer of

Statement

Reference

Uev1A^UAS.cMa/Scer\GAL4^GMR.PF is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, nopo^UAS.cUa

(Ma et al., 2012)

Other

Statement

Reference

Scer\GAL4^ptc-559.1, Uev1A^UAS.cMa, ben^UAS.cUa has anterior crossvein phenotype

(Ma et al., 2013)

Scer\GAL4^ptc-559.1, Traf6^dsRNA.UAS, Uev1A^UAS.cMa, ben^UAS.cUa has eye phenotype

(Ma et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Uev1A^Scer\UAS.cMa and ben^Scer\UAS.cUa under the control of Scer\GAL4^ptc-559.1 results in loss of the anterior cross vein.

Expression of Traf6^{dsRNA.Scer\UAS} suppresses the anterior crossvein loss seen when Uev1A^Scer\UAS.cMa and ben^Scer\UAS.cUa are expressed under the control of Scer\GAL4^ptc-559.1.

Expression of Tak1^NIG.1388R suppresses the anterior crossvein loss seen when Uev1A^Scer\UAS.cMa and ben^Scer\UAS.cUa are expressed under the control of Scer\GAL4^ptc-559.1.

Co-expression of Uev1A^Scer\UAS.cMa and ben^Scer\UAS.cUa in the eye under the control of Scer\GAL4^GMR.PF does not results in any significant phenotype.

Co-expression of Uev1A^Scer\UAS.cMa, ben^Scer\UAS.cUa and Traf6^{dsRNA.Scer\UAS} under the control of Scer\GAL4^GMR.PF results in rough eye with fused ommatidia.

(Ma et al., 2013)

Co-expression of Uev1A^Scer\UAS.cMa does not enhance the small, rough eye phenotype found upon expression of nopo^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PF.

Co-expression of Uev1A^Scer\UAS.cMa and ben^Scer\UAS.cUa significantly enhances the Scer\GAL4^GMR.PF->nopo^Scer\UAS.cUa small rough eye phenotype.

(Ma et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Uev1A^Scer\UAS.cMa

Uev1A^UAS.cMa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Ma

Secondary FlyBase IDs

References (2)

Report Sections

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