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General Information
Symbol
Dmel\Traf6dsRNA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0239951
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dTRAF2-IR
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive Traf6 coding sequences in an inverted repeat to allow cell-targeted generation of dsRNA for RNAi knockdown experiments.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Traf6dsRNA.Scer\UAS in the eye under the control of Scer\GAL4GMR.PF does not results in any significant phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The partial or complete loss of the wing anterior crossvein in flies expressing fmtGD6928 under the control of Scer\GAL4ptc.PU is not suppressed by co-expression of Traf6dsRNA.Scer\UAS.

Expression of Traf6dsRNA.Scer\UAS partially suppresses the wing nicking phenotype seen when krzScer\UAS.T:Ivir\HA1 and dxScer\UAS.T:Zzzz\FLAG are expressed under the control of Scer\GAL4bbg-C96. The resulting flies exhibit loss of L4 vein material.

Expression of Traf6dsRNA.Scer\UAS suppresses the anterior crossvein loss seen when Uev1AScer\UAS.cMa and benScer\UAS.cUa are expressed under the control of Scer\GAL4ptc-559.1.

Co-expression of Uev1AScer\UAS.cMa, benScer\UAS.cUa and Traf6dsRNA.Scer\UAS under the control of Scer\GAL4GMR.PF results in rough eye with fused ommatidia.

Expression of Traf6dsRNA.Scer\UAS under the control of Scer\GAL4Act.PU in the cells surrounding scrib1 clones in the eye-antennal disc significantly suppresses the elimination of the mutant scrib1 clones compared to that seen when the cells surrounding the clone are wild type.

The small-eye phenotype caused by expression of egrScer\UAS.cIa under the control of Scer\GAL4GMR.PF is strongly suppressed by co-expression of Traf6dsRNA.Scer\UAS.

Co-expression of Traf6dsRNA.Scer\UAS has no effect on the mutant eye phenotype caused by expression of Tak1Scer\UAS.cMa under the control of Scer\GAL4hs.2sev.

Co-expression of Traf6dsRNA.Scer\UAS fully suppresses the reduced scutellum phenotype caused by expression of CYLDScer\UAS.cXa under the control of Scer\GAL4pnr-MD237.

Expression of Traf6dsRNA.Scer\UAS (under the control of Scer\GAL4Act5C.PI) using the FLP/FRT system strongly suppresses metastatic behaviour in l(2)gl4 mutants expressing Ras85DV12.Scer\UAS.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Traf6dsRNA.Scer\UAS
Traf6dsRNA.UAS
Name Synonyms
Secondary FlyBase IDs
    References (8)