FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4subdued-c240
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General Information
Symbol
Scer\GAL4subdued-c240
Species
S. cerevisiae
Name
FlyBase ID
FBal0302720
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}subduedc240
Carried in Construct
Also Known As
c240-Gal4
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}subduedc240
    Cytology
    Description

    Insertion of a P{GawB} element within subdued, 32bp downstream of the translational start site.

    (Jang et al., 2015)
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        larval stage
        larval central nervous system | restricted
        (Jang et al., 2015)
        larval multidendritic class III neuron
        (Himmel et al., 2023)
        third instar larval stage
        larval multidendritic class IV neuron
        (Jang et al., 2015)
        adult stage
        adult central nervous system | restricted
        (Jang et al., 2015)
        adult proventriculus | restricted
        (Jang et al., 2015)
        oviduct | restricted
        (Jang et al., 2015)
        spermatheca | restricted
        (Jang et al., 2015)
        adult Malpighian tubule | restricted
        (Jang et al., 2015)
        Additional Information
        Statement
        Reference

        ScerGAL4subdued-c240 drives expression in class IV dendritic arborizing neurons involved in nociception. In addition, expression is observed in some cells of the larval and adult central nervous system. Some non-neural cells are labelled in the proventriculus, oviduct, Malpighian tubule and spermathecum.

        (Jang et al., 2015)
         
        Marker for
        Reflects expression of
        subdued
        (Jang et al., 2015)
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Inactivation of Scer\GAL4subdued-c240-expressing neurons results in an impaired larval nociceptive rolling response to noxious thermal stimuli of 42 or 46[o]C.

        (Jang et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4subdued-c240
        Name Synonyms
        Secondary FlyBase IDs
          References (3)