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General Information
Symbol
Dmel\lncRNA:acal5
Species
D. melanogaster
Name
FlyBase ID
FBal0302948
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

A fraction of acal5 mutant embryos exhibit dorsal closure defects, with holes in either the dorsal or anterior ends of the embryo. No other cuticular defects are seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Suppressed by
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference

lncRNA:acal5/lncRNA:acal5 is a non-suppressor of lethal phenotype of raw2

acal[+]/lncRNA:acal5 is a non-suppressor of lethal phenotype of bsk1

acal[+]/lncRNA:acal5 is a non-suppressor of lethal phenotype of raw2

Other
Phenotype Manifest In
Suppressed by
Statement
Reference
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

bsk1 significantly suppresses the dorsal closure defects and lethality seen in homozygous acal5 mutant embryos.

One copy of acal5 does not suppress the dorsal closure defects and lethality seen in homozygous bsk1 mutant embryos.

One copy of raw2 enhances the embryonic lethality seen in homozygous acal5 mutants, with a quarter of embryos phenocopying the dorsalized phenotype seen in raw2 alone. acal5 does not enhance the homozygous raw2 phenotype.

One copy of acal5 almost completely rescues the dorsal closure defects and lethality seen in aop1 mutant embryos.

One copy of aop1 does not rescue the dorsal closure defects and lethality seen in acal5 mutant embryos.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments

Expression of acalScer\UAS.cRa under the control of Scer\GAL469B results in significant rescue of acal5 dorsal closure defects and reduction of embryonic lethality.

Expression of acalScer\UAS.cRa under the control of Scer\GAL4pnr-MD237 rescues acal5 dorsal closure defects.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
lncRNA:acal5
Name Synonyms
Secondary FlyBase IDs
    References (1)