FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4VT000454
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General Information
Symbol
Scer\GAL4VT000454
Species
S. cerevisiae
Name
FlyBase ID
FBal0308530
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{VT000454-GAL4}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Meadows, 2015.3.13)
Progenitor genotype
Carried in construct
P{VT000454-GAL4}
Cytology
Description

A 2097 base pair fragment from the flanking non-coding or intronic region of CG4341 is fused upstream of a Drosophila synthetic core promoter (DSCP) followed by sequence encoding a GAL4 driver.

(Meadows, 2015.3.13)
Allele components
Component
Use(s)
Regulatory region(s)
VT000454
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult posterior abdominal ganglion neuron
      (Feng et al., 2014)
      adult brain | restricted
      (Feng et al., 2014)
      antennal mechanosensory and motor center
      (Jefferis, 2016.3.4)
      protocerebral bridge
      (Jefferis, 2016.3.4)
      adult subesophageal zone
      (Jefferis, 2016.3.4)
      ventrolateral protocerebrum
      (Jefferis, 2016.3.4)
      fan-shaped body
      (Jefferis, 2016.3.4)
      adult lateral accessory lobe
      (Jefferis, 2016.3.4)
      adult stage | female
      posterior superior medial protocerebrum | restricted
      (Feng et al., 2014)
      Additional Information
      Statement
      Reference

      ScerGAL4VT007068 drives expression in some areas of the adult brain. In females expression in the posterior abdominal ganglion is stronger and labeling in the posterior superior medial protocerebrum is not detectable in males.

      (Feng et al., 2014)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Silencing Scer\GAL4VT000454-expressing neurons renders virgin females sexually unreceptive to males. Elevated levels of egg laying are seen. Activating these neurons has no effect effect on virgin receptivity and does not increase receptivity after mating compared with controls.

      Making Scer\GAL4VT000454-expressing neurons insensitive to sex peptide by expressing SPRGD3236 has no effect on the sexual receptivity of virgin females to males.

      (Feng et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4VT000454
      Name Synonyms
      Secondary FlyBase IDs
        References (3)