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General Information
Symbol
Dmel\maheUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0317103
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of mahe tagged with Tag:HA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of maheScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ey.PU results in a massive reduction in adult eye size in both male and female flies. The larval eye-antennal discs are also significantly smaller than those of controls.

Expression of maheScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ptc.PU results in an enormous decrease in the size of the salivary gland with 100% penetrance. The salivary gland nuclei are much smaller than in controls. Notching is seen at the wing margin, the distance between the L3 and L4 veins is reduced and there is loss of sensory bristles in the scutellum. Suppression of apoptosis does not suppress this loss of bristles.

Expression of maheScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4bbg-C96 has no visible effect on the wing margin.

Expression of maheScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ap.PU results in blistered and notched wings.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference

Scer\GAL4ey.PU, maheUAS.Tag:HA has visible phenotype, suppressible | partially by dx152/dx[+]

Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
Other
Phenotype Manifest In
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference

Scer\GAL4ey.PU, maheUAS.Tag:HA has eye phenotype, suppressible | partially by dx152/dx[+]

Enhancer of
Statement
Reference
Suppressor of
Other
Additional Comments
Genetic Interactions
Statement
Reference

One copy of Df(1)N-54l9 significantly enhances the reduced eye phenotype seen when maheScer\UAS.T:Ivir\HA1 is expressed under the control of Scer\GAL4ey.PU with 100% penetrance.

One copy of dx152 marginally suppresses the reduced eye phenotype seen when maheScer\UAS.T:Ivir\HA1 is expressed under the control of Scer\GAL4ey.PU in 32% of eyes examined.

Expression of maheScer\UAS.T:Ivir\HA1 partially suppresses the highly proliferated eye tissue phenotype seen when NICN.Scer\UAS is expressed under the control of Scer\GAL4ey.PU.

Co-expression of maheScer\UAS.T:Ivir\HA1 and dxScer\UAS.cMa under the control of Scer\GAL4bbg-C96 results in wing margin nicking.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
maheScer\UAS.T:Ivir\HA1
maheUAS.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (1)