FlyBase Allele Report: Dmel\mam[N.UAS]

General Information

Symbol

Dmel\mam^N.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0102513

Feature type

allele

Associated gene

Dmel\mam

Associated Insertion(s)

Carried in Construct

P{UAS-mamN}

Also Known As

UAS-mam^DN, UAS-MamN, UAS-MamDN, UAS-mam^N, UAS-mam-DN

Key Links

Transgenic product class

inframe_deletion

(Helms et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Helms et al., 1999)

Mutagen

in vitro construct

(Helms et al., 1999)

Progenitor genotype

Carried in construct

P{UAS-mamN}

Cytology

Description

A truncated mam open reading frame, ending at nucleotide 3884 (amino acid residue 1043), is driven under the control of UASt sequences. Sequences located carboxy to the first GV region are deleted removing two of the three Gly-Val runs.

(Helms et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

mam

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | embryonic stage, with Scer\GAL4^elav-C155

(Ulvklo et al., 2012)

abnormal neuroanatomy | heat sensitive, with Scer\GAL4^hs.PH

(Yedvobnick et al., 2004)

abnormal size | third instar larval stage, with Scer\GAL4^en.PU

(Slaninova et al., 2016)

visible, with Scer\GAL4^bbg-C96

(Surabhi et al., 2015, Kankel et al., 2007, Yedvobnick et al., 2001)

visible, with Scer\GAL4^GMR.PF

(Helms et al., 1999)

visible, with Scer\GAL4^hs.2sev

(Helms et al., 1999)

visible, with Scer\GAL4^pnr-MD237

(Helms et al., 1999)

visible | adult stage, with Scer\GAL4^pnr-MD237

(Alexander et al., 2006)

visible | adult stage, with Scer\GAL4^pnr-MD237, mam^EP2022.A

(Alexander et al., 2006)

Phenotype Manifest In

apterous-expressing neuron of the lateral cluster of the thorax, with Scer\GAL4^elav-C155

(Ulvklo et al., 2012)

cone cell | P-stage, with Scer\GAL4^pros.PSG

(Blackie et al., 2021)

ectoderm | heat sensitive, with Scer\GAL4^hs.PH

(Yedvobnick et al., 2004)

egg chamber | somatic clone, with Scer\GAL4^Act.PU, Scer\GAL4^Tub.PU

(Vied and Kalderon, 2009)

eye, with Scer\GAL4^dpp.blk1

(Helms et al., 1999)

eye, with Scer\GAL4^GMR.PF

(Helms et al., 1999)

eye, with Scer\GAL4^hs.2sev

(Helms et al., 1999)

female germline stem cell, with Scer\GAL4^C587

(Song et al., 2007)

germarium cap cell, with Scer\GAL4^C587

(Song et al., 2007)

larval neuron | ectopic | heat sensitive, with Scer\GAL4^hs.PH

(Yedvobnick et al., 2004)

macrochaeta, with Scer\GAL4^pnr-MD237

(Helms et al., 1999)

macrochaeta | ectopic, with Scer\GAL4^dpp.blk1

(Helms et al., 1999)

macrochaeta | ectopic, with Scer\GAL4^pnr-MD237

(Helms et al., 1999)

mesonotum, with Scer\GAL4^pnr-MD237

(Alexander et al., 2006)

mesonotum, with Scer\GAL4^pnr-MD237, mam^EP2022.A

(Alexander et al., 2006)

microchaeta, with Scer\GAL4^pnr-MD237

(Alexander et al., 2006, Helms et al., 1999)

microchaeta, with Scer\GAL4^pnr-MD237, mam^EP2022.A

(Alexander et al., 2006)

microchaeta | ectopic, with Scer\GAL4^pnr-MD237

(Helms et al., 1999)

ommatidium, with Scer\GAL4^dpp.blk1

(Helms et al., 1999)

sensory mother cell, with Scer\GAL4^pnr-MD237

(Helms et al., 1999)

wing, with Scer\GAL4^bbg-C96

(Kankel et al., 2007, Yedvobnick et al., 2001, Helms et al., 1999)

wing, with Scer\GAL4^dpp.blk1

(Helms et al., 1999)

wing disc posterior compartment | third instar larval stage, with Scer\GAL4^en.PU

(Slaninova et al., 2016)

wing margin, with Scer\GAL4^bbg-C96

(Surabhi et al., 2015)

wing margin bristle, with Scer\GAL4^bbg-C96

(Helms et al., 1999)

wing vein L3, with Scer\GAL4^dpp.blk1

(Helms et al., 1999)

Detailed Description

Statement

Reference

Expression of mam^N.Scer\UAS under the control of Scer\GAL4^en.PU results in a significant decrease in size of the third instar wing disc posterior compartment, as compared to controls.

(Slaninova et al., 2016)

Expression of mam^N.Scer\UAS under the control of Scer\GAL4^bbg-C96 results in severe serration of the wing margin.

(Surabhi et al., 2015)

Embryos expressing mam^N.Scer\UAS under the control of Scer\GAL4^elav-C155 have an increased number of "Ap" neurons in the NB5-6T lineage.

(Ulvklo et al., 2012)

Males expressing mam^N.Scer\UAS under the control of Scer\GAL4^Abd-B-LDN show normal genitalia rotation.

(Lee et al., 2011)

Follicle stem cells clones expressing mam^N.Scer\UAS under the control of both Scer\GAL4^Act and Scer\GAL4^tub simultaneously persist in the ovariole approximately as well as control clones over a 14 day period. Egg chamber fusions are seen in ovarioles carrying these clones.

(Vied and Kalderon, 2009)

Flies expressing mam^N.Scer\UAS under the control of Scer\GAL4^bbg-C96 show a fully-penetrant wing-nicking phenotype.

(Kankel et al., 2007)

A reduction of mam protein levels in elB^3.3.1 noc^d64 double mutant ey clones, through expression of mam^N.Scer\UAS under the control of Scer\GAL4^{Scer\FRT.Act5C} reduces the frequency of overgrowths per adult fly from 51.5% to 4.8%, without affecting cell viability.

(Luque and Milan, 2007)

The number of cap cells and germline stem cells in the ovaries of 2 day old females expressing mam^N.Scer\UAS under the control of Scer\GAL4^C587 is significantly reduced compared to wild type.

(Song et al., 2007)

Expression of mam^N.Scer\UAS under the control of Scer\GAL4^pnr-MD237 results in a 100% penetrant loss of many microchaetes along the central anterior/posterior axis of the notum (whereas mam^N.Scer\UAS heterozygotes show nota with a normal pattern of microchaetes). This phenotype is partially suppressed in flies also heterozygous for mam^EP2022.A.

(Alexander et al., 2006)

mam^N.Scer\UAS; Scer\GAL4¹¹⁵¹ pupae have normal numbers of dorso-ventral indirect flight muscle founder cells.

(Dutta et al., 2004)

Expression of mam^N.Scer\UAS under the control of Scer\GAL4^hs.PH between 2 and 6 hours of development results in a neurogenic phenotype with a large number of neurons forming at the expense of ectoderm. Expression of mam^N.Scer\UAS under the control of Scer\GAL4^hs.PH between 6 and 8 hours of development has no effect on GMC-1 division.

(Yedvobnick et al., 2004)

mam^N.Scer\UAS when driven by Scer\GAL4^GMR.PF or Scer\GAL4^hs.2sev produces a completely penetrant rough eye phenotype. mam^N.Scer\UAS/Scer\GAL4^pnr-MD237 adults exhibit microchaetae loss between the dorsocentral macrochaetae; the phenotype varies from bald nota to those sparsely populated with bristles. The more anterior/lateral regions can contain higher than normal microchaetae densities. These flies also exhibit additional macrochaetae, twin shafts and some microchaetae sites, and twin to quadruple shafts at some (primarily scutellar) macrochaetae sites. When the pupal notum is examined in mam^N.Scer\UAS/Scer\GAL4^pnr-MD237 animals, an increase in Sensory Organ Precursors (SOPs) are seen. Clusters of neurons are observes at each microchaetae site. When mam^N.Scer\UAS is driven by Scer\GAL4^C96 wing nicks are seen and there is a loss of wing margin bristles. The most significant margin loss occurs along distal and posterior wing regions. In some regions the margin remains largely intact, though most bristles are missing. When mam^N.Scer\UAS is driven by Scer\GAL4^dpp.blk1, a range of phenotypes are seen. Macrochaetae duplications thickened wing vein 3, a loss of material at the anterior/posterior boundary of the wing and small rough eyes can be seen.

(Helms et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by mahe^UAS.Tag:HA/Scer\GAL4^bbg-C96

(Surabhi et al., 2015)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by CG14767^c06428/CG14767[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by klu^d00059/klu[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Sin3A[+]/Sin3A^d07432

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by sca[+]/sca^d09400

(Kankel et al., 2007)

Scer\GAL4^pnr-MD237, mam^N.UAS has visible | adult stage phenotype, enhanceable by Delta^EP3816.A, Scer\GAL4^pnr-MD237

(Alexander et al., 2006)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Psn^E280A.UAS, Scer\GAL4^bbg-C96

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(2R)nap1

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(3R)3450

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(3R)Delta-BX12

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(3R)XTA1

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by In(2LR)Px⁴

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by sno^71e1

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(1)N-8

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(1)JA26

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(2L)cl-h3

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(2R)Chi^g230

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(2R)PC4

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by sgg^UAS.cSa/Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by H^UAS.cGa, Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Scer\GAL4^bbg-C96/fz2^{ECD.GPI.UAS.Tag:MYC}

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Ser^rev6-1

(Helms et al., 1999)

Scer\GAL4^GMR.PF, mam^N.UAS has visible phenotype, enhanceable by Delta^BX9

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Df(1)N-54l9

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by N^nd-1

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Delta^BX9

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Ser^Bd-3

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by Su(H)¹⁶

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by dx¹

(Helms et al., 1999)

Scer\GAL4^dpp.blk1, mam^N.UAS has visible phenotype, enhanceable by Df(1)N-54l9

(Helms et al., 1999)

Scer\GAL4^dpp.blk1, mam^N.UAS has visible phenotype, enhanceable by Delta^BX9

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by wg^l-17

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by arm¹

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, enhanceable by ct^53d

(Helms et al., 1999)

NOT Enhanced by

Statement

Reference

Scer\GAL4^pnr-MD237, mam^N.UAS has visible | adult stage phenotype, non-enhanceable by RpL13A^EP3614.A, Scer\GAL4^pnr-MD237

(Alexander et al., 2006)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, non-enhanceable by sgg^M11

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, non-enhanceable by Df(3R)Espl1

(Helms et al., 1999)

Suppressed by

Statement

Reference

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by CG14709[+]/Mrp4^d05358

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by GPHR^c06331/CG8090[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by mts^c02035/mts[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by f06222^f06222/f06222[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by Df(1)v-L15

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by Df(3R)P14

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by H¹

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by Delta^UAS.cJa, Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by N^int.G.UAS, Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype, suppressible by Scer\GAL4^bbg-C96/Ser^UAS.cGa

(Helms et al., 1999)

NOT suppressed by

Statement

Reference

Scer\GAL4^pnr-MD237, mam^N.UAS has visible | adult stage phenotype, non-suppressible by RpL13A^EP3614.A, Scer\GAL4^pnr-MD237

(Alexander et al., 2006)

Suppressor of

Statement

Reference

Scer\GAL4^FRT.Act5C/mam^N.UAS is a suppressor of increased cell number phenotype of elB^3.3.1, noc^d64

(Luque and Milan, 2007)

Scer\GAL4^FRT.Act5C/mam^N.UAS is a suppressor of neoplasia | adult stage phenotype of elB^3.3.1, noc^d64

(Luque and Milan, 2007)

Other

Statement

Reference

Df(3R)Tl-P, Scer\GAL4^bbg-C96, mam^N.UAS has visible phenotype

(Yedvobnick et al., 2001)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^bbg-C96, mam^N.UAS has wing margin phenotype, enhanceable by mahe^UAS.Tag:HA/Scer\GAL4^bbg-C96

(Surabhi et al., 2015)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by CG14767^c06428/CG14767[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by klu^d00059/klu[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Sin3A[+]/Sin3A^d07432

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by sca[+]/sca^d09400

(Kankel et al., 2007)

Scer\GAL4^pnr-MD237, mam^N.UAS has mesothoracic tergum & microchaeta phenotype, enhanceable by Delta^EP3816.A, Scer\GAL4^pnr-MD237

(Alexander et al., 2006)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Psn^E280A.UAS, Scer\GAL4^bbg-C96

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(2R)PC4

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(2R)nap1

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(3R)3450

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(3R)Delta-BX12

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(3R)XTA1

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by In(2LR)Px⁴

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by sno^71e1

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(1)N-8

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(1)JA26

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(2L)cl-h3

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(2R)Chi^g230

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by sgg^UAS.cSa/Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing margin bristle phenotype, enhanceable by H^UAS.cGa, Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by H^UAS.cGa, Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Ser^rev6-1

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing margin bristle phenotype, enhanceable by Ser^rev6-1

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Df(1)N-54l9

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing margin bristle phenotype, enhanceable by Df(1)N-54l9

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by N^nd-1

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing margin bristle phenotype, enhanceable by N^nd-1

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, enhanceable by Delta^BX9

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing margin bristle phenotype, enhanceable by Delta^BX9

(Helms et al., 1999)

NOT Enhanced by

Statement

Reference

Scer\GAL4^pnr-MD237, mam^N.UAS has mesothoracic tergum & microchaeta phenotype, non-enhanceable by RpL13A^EP3614.A, Scer\GAL4^pnr-MD237

(Alexander et al., 2006)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-enhanceable by Su(H)^UAS.cGa/Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-enhanceable by Scer\GAL4^bbg-C96/dx^UAS.cMa

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-enhanceable by Su(H)⁸

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-enhanceable by gro^E48

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-enhanceable by dsh³

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-enhanceable by pan^13a

(Helms et al., 1999)

Suppressed by

Statement

Reference

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, suppressible by CG14709[+]/Mrp4^d05358

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, suppressible by GPHR^c06331/CG8090[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, suppressible by mts^c02035/mts[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, suppressible by f06222^f06222/f06222[+]

(Kankel et al., 2007)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, suppressible by Df(1)v-L15

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, suppressible by Df(3R)P14

(Yedvobnick et al., 2001)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, suppressible by dsh^UAS.cAa

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, suppressible by Scer\GAL4^bbg-C96/arm^{S10.UAS.Tag:MYC}

(Helms et al., 1999)

NOT suppressed by

Statement

Reference

Scer\GAL4^pnr-MD237, mam^N.UAS has mesothoracic tergum & microchaeta phenotype, non-suppressible by RpL13A^EP3614.A, Scer\GAL4^pnr-MD237

(Alexander et al., 2006)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-suppressible by dsh³

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-suppressible by pan^13a

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-suppressible by Scer\GAL4^bbg-C96/dx^UAS.cMa

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-suppressible by Su(H)^UAS.cGa/Scer\GAL4^bbg-C96

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-suppressible by Scer\GAL4^bbg-C96/arm^{S2.UAS.Tag:MYC}

(Helms et al., 1999)

Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype, non-suppressible by Scer\GAL4^bbg-C96/pan^UAS.cWa

(Helms et al., 1999)

Suppressor of

Statement

Reference

mam^N.UAS/Scer\GAL4^Abd-B-LDN is a suppressor | partially of male genitalia phenotype of Uvrag^KG04163/Uvrag^B21

(Lee et al., 2011)

Scer\GAL4^FRT.Act5C/mam^N.UAS is a suppressor of eye-antennal disc | somatic clone phenotype of elB^3.3.1, noc^d64

(Luque and Milan, 2007)

Scer\GAL4^FRT.Act5C/mam^N.UAS is a suppressor of adult head capsule | somatic clone phenotype of elB^3.3.1, noc^d64

(Luque and Milan, 2007)

mam^N.UAS/Scer\GAL4^bbg-C96 is a suppressor of wing margin bristle phenotype of Ser^rev6-1

(Helms et al., 1999)

mam^N.UAS/Scer\GAL4^bbg-C96 is a suppressor of wing sensillum phenotype of Scer\GAL4^bbg-C96, Su(H)^UAS.cGa

(Helms et al., 1999)

NOT Suppressor of

Statement

Reference

mam^N.UAS, Scer\GAL4^bbg-C96 is a non-suppressor of wing sensillum phenotype of N^int.G.UAS, Scer\GAL4^bbg-C96

(Helms et al., 1999)

Other

Statement

Reference

Df(3R)Tl-P, Scer\GAL4^bbg-C96, mam^N.UAS has wing phenotype

(Yedvobnick et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of mahe^{Scer\UAS.T:Ivir\HA1} moderately enhances the wing margin serration seen when mam^N.Scer\UAS is expressed under the control of Scer\GAL4^bbg-C96. A completely penetrant wing notching phenotype is also seen.

(Surabhi et al., 2015)

Expression of mam^N.Scer\UAS using Scer\GAL4^Abd-B-LDN partially rescues the genital rotation defect in Uvrag^KG04163/Uvrag^B21 males.

(Lee et al., 2011)

The wing nicking phenotype caused by expression of mam^N.Scer\UAS under the control of Scer\GAL4^bbg-C96 is dominantly suppressed by CG14709^d05358, CG8090^c06331, mts^c02035 or f06222^f06222.

The wing nicking phenotype caused by expression of mam^N.Scer\UAS under the control of Scer\GAL4^bbg-C96 is dominantly enhanced by CG14767^c06428, klu^d00059, Sin3A^d07432 or sca^d09400.

(Kankel et al., 2007)

The notal microchaete loss phenotype induced by expression of mam^N.Scer\UAS under the control of Scer\GAL4^pnr-MD237 is enhanced in flies heterozygous for Dl^EP3816.A.

(Alexander et al., 2006)

The rough eye phenotype produced by mam^N.Scer\UAS when driven by Scer\GAL4^GMR.PF or Scer\GAL4^hs.2sev is mildly enhanced by Dl^unspecified. The addition of N^nd-1/Y, Df(1)N-54l9, Dl^BX9, Ser^Bd-3, Ser^rev6-1, dx¹ sgg^Scer\UAS.cSa or Su(H)¹⁶ produces enhanced wing margin effects in flies expressing mam^N.Scer\UAS driven by Scer\GAL4^C96. The wing nicking phenotype is unaffected by the addition of Su(H)⁸, pan^Scer\UAS.cWa or arm^{S2.Scer\UAS.T:Hsap\MYC}. The wing nicking phenotype is suppressed by the addition of H¹ and arm^{S10.Scer\UAS.T:Hsap\MYC}. The addition of wg^l-17 or arm¹ to mam^N.Scer\UAS, Scer\GAL4^C96 flies also enhances the wing phenotype in a partially penetrant manner, exhibiting loss of additional wing blade material along the posterior margin and bristle loss along the anterior margin. A small percentage of more severe strap wings is also observed in the case of wg^l-17. The wing nicking phenotype is unaffected by the addition of dsh³, sgg^M11 or pan^13a. The addition of fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC} also enhances the phenotype, producing a wide range of phenotypes, including severe loss of blade material. ct^53d also enhances the wing nicking phenotype. The phenotype caused when mam^N.Scer\UAS is driven by Scer\GAL4^dpp.blk1 can be enhanced by the addition of mam¹⁰, Df(1)N-54l9 or Dl^BX9. The addition of Dl^Scer\UAS.cJa dsh^Scer\UAS.cAa or N^{int.G.Scer\UAS} to mam^N.Scer\UAS, Scer\GAL4^C96 flies, strongly suppresses its wing nicking phenotype. Ser^Scer\UAS.cGa weakly suppresses the phenotype. H^Scer\UAS.cGa enhances the phenotype and dx^Scer\UAS.cMa and Su(H)^Scer\UAS.cGa have no effect. Does not suppress the wing bristle phenotype see in N^{int.G.Scer\UAS}, Scer\GAL4^C96 flies. Mildly suppresses the wing bristle phenotype see in flies carrying Su(H)^Scer\UAS.cGa or Ser^Scer\UAS.cGa driven by Scer\GAL4^C96.

(Helms et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^hs.PH/mam^N.UAS rescues mam⁴⁴

(Yedvobnick et al., 2004)

Fails to rescue

Scer\GAL4^Act.PU, mam^N.UAS, Scer\GAL4^Tub.PU fails to rescue mam⁸

(Vied and Kalderon, 2009)

Scer\GAL4^hs.PH/mam^N.UAS fails to rescue mam⁹

(Yedvobnick et al., 2004)

Comments

The mam⁸ follicle stem cell clone loss is not rescued by expression of mam^N.Scer\UAS under the control of both Scer\GAL4^Act and Scer\GAL4^tub simultaneously.

(Vied and Kalderon, 2009)

The loss of asymmetric division in GMC-1 of the RP2/sib lineage seen in mam⁴⁴ embryos is rescued by expression of mam^N.Scer\UAS under the control of Scer\GAL4^hs.PH between 6 and 8 hours of development. The loss of asymmetric division in GMC-1 of the RP2/sib lineage and the neurogenic phenotype seen in mam⁹ embryos is not rescued by expression of mam^N.Scer\UAS under the control of Scer\GAL4^hs.PH between 6 and 8 hours of development.

(Yedvobnick et al., 2004)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

26672

w^*; P{UAS-mamN}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

mam^N.Scer\UAS

mam^N.UAS

Name Synonyms

Secondary FlyBase IDs

References (27)

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