FlyBase Allele Report: Dmel\Rtca[UAS.cSa]

General Information

Symbol

Dmel\Rtca^UAS.cSa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Song

FlyBase ID

FBal0318444

Feature type

allele

Associated gene

Dmel\Rtca

Associated Insertion(s)

Carried in Construct

P{UAS-Rtca.S}

Also Known As

UAS-Rtca

Key Links

Transgenic product class

wild_type

(Song et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Song et al., 2015)

Mutagen

in vitro construct

(Song et al., 2015)

Progenitor genotype

Carried in construct

P{UAS-Rtca.S}

Cytology

Description

UASt regulatory sequences drive expression of the entire Rtca coding sequence.

(Song et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Rtca

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage, with Scer\GAL4^ppk.PG

(Wang et al., 2025)

abnormal wound healing | larval stage, with Scer\GAL4^ppk.PG

(Wang et al., 2025)

decreased cell growth rate | second instar larval stage | conditional, with Scer\GAL4^ppk.PU

(Song et al., 2015)

decreased cell growth rate | second instar larval stage | conditional, with Scer\GAL4^tey-5053A

(Song et al., 2015)

Phenotype Manifest In

axon | larval stage, with Scer\GAL4^ppk.PG

(Wang et al., 2025)

larval dorsal multidendritic neuron ddaC, with Scer\GAL4^ppk.PG

(Wang et al., 2025)

Detailed Description

Statement

Reference

Overexpression (Rtca^Scer\UAS.cSa) in class IV da neurons (Scer\GAL4^ppk.PU) or motor neurons (Scer\GAL4^tey-5053A) reduces axon regenerative potential.

(Song et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Rtca^UAS.cSa, Scer\GAL4^ppk.PG has abnormal wound healing | larval stage phenotype, suppressible by Rab10^JF02058, Scer\GAL4^ppk.PG

(Wang et al., 2025)

Rtca^UAS.cSa, Scer\GAL4^ppk.PG has abnormal neuroanatomy | larval stage phenotype, suppressible by Rab10^JF02058, Scer\GAL4^ppk.PG

(Wang et al., 2025)

Suppressor of

Statement

Reference

Rtca^UAS.cSa/Scer\GAL4^ppk.PU is a suppressor of increased cell growth rate | second instar larval stage | conditional phenotype of Pten^MGH6

(Song et al., 2015)

Phenotype Manifest In

Suppressed by

Statement

Reference

Rtca^UAS.cSa, Scer\GAL4^ppk.PG has larval dorsal multidendritic neuron ddaC phenotype, suppressible by Rab10^JF02058, Scer\GAL4^ppk.PG

(Wang et al., 2025)

Rtca^UAS.cSa, Scer\GAL4^ppk.PG has axon | larval stage phenotype, suppressible by Rab10^JF02058, Scer\GAL4^ppk.PG

(Wang et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Overexpression of Rtca^Scer\UAS.cSa driven by Scer\GAL4^ppk.PU abolishes enhancement of axon regeneration seen in Pten^MGH6/Pten^MGH6 larvae.

(Song et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Rtca^Scer\UAS.cSa

Rtca^UAS.cSa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Song

Secondary FlyBase IDs

References (2)

Report Sections

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