FB2026_02 , released June 18, 2026
Allele: Dmel\AcfTag:TY1,EGFP,Tag:FLAG
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General Information
Symbol
Dmel\AcfTag:TY1,EGFP,Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0319818
Feature type
allele
Associated gene
Dmel\Acf
Associated Insertion(s)
Carried in Construct
P{Acf1-GFP.fos}
Key Links
Transgenic product class
genomic_DNA
(Börner et al., 2016)
wild_type
(Börner et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Börner et al., 2016)
wild_type
(Börner et al., 2016)
Mutagen
in vitro construct
(Börner et al., 2016)
Progenitor genotype
Carried in construct
P{Acf1-GFP.fos}
Cytology
Description

Genomic fragment containing full-length Acf. A 2xTY1-EGFP-3xFLAG-tag has been inserted at the C-terminal end of the Acf open reading frame.

(Börner et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
Acf
Encoded product / tool
Acf
Tagged with
EGFP
Tag:FLAG
Tag:TY1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      oogenesis & adult stage | female
      female germline cell
      (Börner et al., 2016)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Acf
      (Börner et al., 2016)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of two copies of AcfT:Scer\TY1,T:Avic\GFP-EGFP,T:Zzzz\FLAG in a wild type background results in a small but significant increase in egg chamber cell packaging defects, including compound egg chambers, but no significant increase in apoptotic egg chambers, as compared to wild type.

      (Börner et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of two copies of Chrac-16T:Scer\TY1,T:Disc\RFP-mCherry,T:Zzzz\FLAG and two copies of AcfT:Scer\TY1,T:Avic\GFP-EGFP,T:Zzzz\FLAG in a wild type background results in an increased number of apoptotic egg chambers, and no significant difference in egg chamber cell packaging defects, as compared with flies expressing two copies of AcfT:Scer\TY1,T:Avic\GFP-EGFP,T:Zzzz\FLAG.

      (Börner et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      AcfTag:TY1,EGFP,Tag:FLAG rescues Acf7

      (Börner et al., 2016)
      Partially rescues

      AcfTag:TY1,EGFP,Tag:FLAG partially rescues Acf1

      (Börner et al., 2016)
      Comments

      The presence of AcfT:Scer\TY1,T:Avic\GFP-EGFP,T:Zzzz\FLAG/AcfT:Scer\TY1,T:Avic\GFP-EGFP,T:Zzzz\FLAG fully rescues the egg chamber apoptotic defects of Acf1/Acf1 and Acf7/Acf7 mutants, and partially rescues the egg chamber cell packaging defects of Acf1/Acf1 mutants.

      (Börner et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      AcfT:Scer\TY1,T:Avic\GFP-EGFP,T:Zzzz\FLAG
      AcfTag:TY1,EGFP,Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)